Sökning: "PR3"

Visar resultat 1 - 5 av 27 avhandlingar innehållade ordet PR3.

  1. 1. Membrane traffic in neutrophils and neutrophil-like cells

    Författare :Susanne Bauer; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infections; membrane traffic; Hematologi; extracellular fluids; Haematology; Medicin människa och djur ; Medicine human and vertebrates ; CD177; extracellulära vätskor; PR3; phagocytosis; Streptococcus pyogenes; Infektioner; neutrophils;

    Sammanfattning : The neutrophil constitutes the first line of defence against invading organisms and its primary function is to recognize, phagocytose and kill intruding microorganisms. In this thesis, the membrane traffic in neutrophils and neutrophil-like cells was studied. Non-opsonised S. LÄS MER

  3. 2. Protease proforms as hematopoietic regulators

    Författare :Stefan Sköld; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; granulopoiesis proform PR3 NO ribonucleotide reductase; extracellular fluids; Haematology; Hematologi; extracellulära vätskor;

    Sammanfattning : A common feature in myeloid leukemia is suppression of normal hematopoiesis, leading to infections, bleeding and anemia. It has been suggested for a long time that leukemic cells possess a growth-advantage by overproducing an inhibitor - a leukamia associated inhibitor. LÄS MER

  4. 3. Proteinase 3 and Neutrophil Apoptosis in ANCA-Associated Systemic Vasculitis

    Författare :Mohamed AbdGawad; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wegener’s granulomatosis; anti-neutrophil cytoplasmic antibody ANCA . Proteinase 3 PR3 ; myeloperoxidase MPO . Flowcytometry FACS . Vasculitis.; microscopic polyangitis;

    Sammanfattning : ANCA-Associated Systemic Vasculitis (AASV) is characterized by leukocytoclasis- dying neutrophils surrounding small blood vessels. Previous studies have shown increased plasma PR3 and increased proportion of neutrophils expressing plasma membrane-associated PR3 (mPR3+). LÄS MER

  5. 4. Kinin System Activation in Vasculitis

    Författare :Robin Kahn; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kinin receptors; inflammation; vasculitis; proteinase 3; neutophils; anti-neutrophil-cytoplasmic antibodies; Kinin;

    Sammanfattning : The kinin system is activated when high-molecular-weight kininogen (HK) is cleaved by plasma kallikrein thus generating bradykinin. Bradykinin is a potent proinflammatory peptide that induces plasma leakage, blood pressure drop, liberation of inflammatory cytokines and pain. LÄS MER

  7. 5. Diagnostic and prognostic aspects of anti-neutrophil cytoplasmic antibodies in systemic vasculitis

    Författare :Daina Selga; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serologi; serology; epitope; Wegener s granulomatosis; microscopic polyangiitis; polyarteritis nodosa; capture ELISA; Immunology; anti-neutrophil cytoplasmic antibody; proteinase 3; vasculitis; nephrology; Urologi; nefrologi; Urology;

    Sammanfattning : Primary systemic vasculitis is associated with a high mortality if left untreated and it is essential to make the diagnosis before permanent organ damage has occurred. In this thesis the diagnostic and prognostic significance of anti-neutrophil cytoplasmic antibodies (ANCA) in systemic vasculitis is investigated. LÄS MER