Sökning: "PDGF-C"
Visar resultat 6 - 10 av 10 avhandlingar innehållade ordet PDGF-C.
6. Studies of VEGF-B and novel PDGFs in tumorigenesis and angiogenesis
Sammanfattning : The family of VEGF/PDGF growth factors and their receptors are important regulators of tumorigenesis and angiogenesis. VEGFs have been shown to play important roles in development of both blood and lymphatic vessels by effect on endothelia cells. LÄS MER
7. Proteolytic activation and biological functions of the novel PDGFs
Sammanfattning : The platelet-derived growth factors (PDGFs) and their cell surface receptors regulate growth and migration of connective tissue cells of both the vascular network and other organ systems. They are known to be important for normal development and processes, such as wound healing and angiogenesis, but have also been implicated in many pathological conditions, such as malignancies and fibrotic disease. LÄS MER
8. Studies of the novel PDGFs, focusing on PDGF-D
Sammanfattning : Thirty years ago the classical platelet-derived growth factors (PDG17s), PDGF-A and PDGF-B were discovered. For a long time they were thought to be the only PDG17 isoforms to exist, but recently two novel PDGF molecules were identified, namely PDGF-C and PDGF-D. LÄS MER
9. The role of PDGF-A in lung development, injury and repair
Sammanfattning : The developmental processes that take place during embryogenesis depend on a great number of proteins that are important for cell-to-cell communication. Platelet-derived growth factors are known to be important for epithelial-mesenchymal interactions during development and organogenesis. LÄS MER
10. A PDGFRalpha perspective on PDGF signalling in developmental and pathological processes
Sammanfattning : Platelet-derived growth factors PDGFs are a family of ligands and receptors that regulate multiple processes of paramount importance during embryonic development. They are also involved in several pathological events, spanning from tumours to fibrotic diseases. LÄS MER
