Sökning: "Oscar Verho"
Hittade 3 avhandlingar innehållade orden Oscar Verho.
1. Transition metal-catalyzed hydrogen transfer processes
Sammanfattning : The first part describes the synthesis of new analogues of Bäckvall’s catalyst with varying electronic properties and their application in the racemization of sec-alcohols. The racemization involves two key steps: (i) β-hydride elimination (dehydrogenation of the alcohol) and (ii) hydride re-addition to the intermediate ketone. LÄS MER
2. Transition Metal-Catalyzed Redox Reactions : A Journey from Homogeneous Ruthenium to Heterogeneous Palladium Catalysis
Sammanfattning : The first part of the thesis covers the development and utilization of electronically modified (pentaarylcyclopentadienyl)Ru-complexes in the racemization of secondary alcohols. This study revealed that the electronic properties of the substrate were the main factors dictating whether β-hydride elimination or hydride re-addition becomes the rate-determining step of the racemization process. LÄS MER
3. Palladium Catalysis in Directed C-H Bond Activation and Cycloisomerisation Reactions
Sammanfattning : The main focus of this thesis concerns the development of Pd(II)-catalysed synthetic methodologies for the preparation of biologically active compounds.In the first part (paper I-III), unactivated C–H bonds of a cyclobutane derivative are selectively functionalised using a directing group starting from the feedstock compound verbenone (paper I). LÄS MER