Sökning: "Octanol water partitioning"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Octanol water partitioning.

  1. 1. Partitioning of Drugs and Lignin Precursor Models into Artificial Membranes

    Författare :Elisabet Boija; Gunnar Johansson; Per Lundahl; Christine Lagerquist Hägglund; Marja-Liisa Riekkola; Uppsala universitet; []
    Nyckelord :Biochemistry; Bilayer disk; Capillary electrophoresis; Detergent; Drug; Electrostatic interaction; Hydrophobic interaction; Immobilized liposome chromatography; Lignin; Lignin precursor model; Liposome; Membrane model; Octanol water partitioning; Partitioning; Phospholipid; Phospholipid bilayer; Sterol; Biokemi;

    Sammanfattning : The main aim of this thesis was to characterize membrane-solute interactions using artificial membranes in immobilized liposome chromatography or capillary electrophoresis. The partitioning of a solute into a cell membrane is an essential step in diffusion across the membrane. LÄS MER

  3. 2. In silico methods to prioritize chemicals with high exposure potential

    Författare :Efstathios Reppas Chrysovitsinos; Matthew MacLeod; Anna Sobek; Michael Matthies; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; free energy relationship; solvation parameters; polymers; materials; partitioning; octanol; Arctic contaminants; AMAP; POPs; Stockholm Convention; vPvB; REACH; OECD; QSAR; planetary boundaries; persistence; bioaccumulation; long-range transport; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : Chemicals offer a wide range of desired functions and are used in a variety of consumer goods and industrial sectors. The number of individual synthetic organic chemicals produced and the total global chemical production volume are increasing. LÄS MER

  4. 3. Partitioning and persistence of volatile methylsiloxanes in aquatic environments

    Författare :Dimitrios Panagopoulos; Matthew MacLeod; Annika Jahnke; Amelie Kierkegaard; Whelan Mick; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; siloxanes; organic carbon; sediment; partitioning; persistence; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : The presence of volatile methylsiloxanes (VMS) in the environment has raised concerns among environmental chemists and regulators about their persistence and the risks they may pose to the environment. This thesis explores the partitioning and persistence of VMS in aquatic environments. LÄS MER

  5. 4. Tools for Evaluating the Fate and Bioaccumulation of Organic Compounds in Aquatic Ecosystems

    Författare :Erick Nfon; Ian Cousins; Jan Hendriks; Stockholms universitet; []
    Nyckelord :Baltic Sea; Biomagnification; Exposure; Food web; Fugacity model; Stable isotopes; Organic contaminants; NATURAL SCIENCES; NATURVETENSKAP; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : The bioaccumulation of organic contaminants in aquatic ecosystems has been a key focus in environmental toxicology over the last decades. Bioaccumulation is a key concept in ecological risk assessments since it controls the internal dose of potential environmental contaminants. LÄS MER

  7. 5. Partition chromatography of drugs on immobilized liposomes and biomembranes : A method applicable to screening in drug design

    Författare :Farideh Beigi; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : One of the main pathways for drug passage into cells is diffusion across the lipid bilayer ofthe cell membrane. A key factor in this process is the drug partitioning into the bilayer, whichcan be translated into a retention in a chromatographic system. LÄS MER