Sökning: "Nkx"

Hittade 4 avhandlingar innehållade ordet Nkx.

  1. 1. Optical projection tomography based 3D-spatial and quantitative assessments of the diabetic pancreas

    Författare :Tomas Alanentalo; Ulf Ahlgren; Raphael Scharfmann; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nkx; development; optical projection tomography; 3D visualisation; pancreas; beta-cell mass; insulitis; diabetes; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : The gastrointestinal tract comprises a number of digestive organs including the stomach and pancreas. The stomach is involved in the digestion and short term storage of food while the pancreas is a mixed endocrine and exocrine gland which provides the body with hormones and enzymes essential for nutritional utilisation. LÄS MER

  3. 2. The role of Nkx proteins neuronal and glial specification

    Författare :Anna Vallstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During development, different classes of neurons and glia are generated from proliferative progenitor cells lining the ventricles of the brain and the lumen of the spinal cord. A central issue in developmental neuroscience is to understand the mechanisms by which these cells are generated in space and over time. LÄS MER

  4. 3. Spleno-pancreatic development assessed by 3D molecular imaging

    Författare :Amir Asayesh; Ulf Ahlgren; Beatriz Sosa-Pineda; Umeå universitet; []
    Nyckelord :Cell biology; Spleen; Pancreas; Imaging; Development; Cellbiologi; miljömedicinsk utvecklingsbiologi; Developmental Biology;

    Sammanfattning : The development of different organs and tissues along the gastrointestinal tract, including the pancreas, depends on signalling between the endoderm and the adjacent mesenchyme. The Nkx gene Bapx1 is involved in spatial control of organ-positioning in the spleno-pancreatic region, and deficiency in this gene results in unacceptable proximity of the splenic mesenchyme to the pancreas. LÄS MER

  5. 4. Spatial and temporal mechanisms of cell fate determination in the developing CNS

    Författare :José Dias; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The generation of neural cell diversity in the developing central nervous system relies on mechanisms that provide spatial and temporal information to neural progenitor cells. The deployment of morphogen gradients is an important strategy to impart spatial information to the field of responding cells. LÄS MER