Sökning: "Neurotrophic factor"
Visar resultat 1 - 5 av 157 avhandlingar innehållade orden Neurotrophic factor.
1. Neurotrophic Factor Receptors in the Normal and Injured Visual System : Focus on Retinal Ganglion Cells
Sammanfattning : The focus of this thesis is the life and death of adult retinal ganglion cells (RGCs). RGCs are neurons that convey visual information from the retina to higher centers in the brain. LÄS MER
2. The use of adipose derived stem cells in spinal cord and peripheral nerve repair
Sammanfattning : Clinically, injuries affecting the spinal cord or peripheral nerves can leave those affected with severe disability and, at present, there are limited options for treatment. Peripheral nerve injury with a significant gap between the proximal and distal stumps is currently treated with autologous nerve grafting but this is limited by availability of donor nerve and has associated morbidities. LÄS MER
3. Transplantation of mesenchymal stem cells and injections of microRNA as therapeutics for nervous system repair
Sammanfattning : Traumatic injuries to the spinal cord (SCI) and peripheral nerve (PNI) affect several thousand people worldwide every year. At present, there is no effective treatment for SCI and despite continuous improvements in microsurgical reconstructive techniques for PNI, many patients are still left with permanent, devastating neurological dysfunction. LÄS MER
4. Experimental Studies of BMP Signalling in Neuronal Cells
Sammanfattning : The developing nervous system depends largely on extracellular cues to shape its complex network of neurons. Classically, neurotrophins are known to be important mediators in this process. LÄS MER
5. Regeneration of Peripheral Nerves. The role of protein kinases, with emphasis on neurotrophic factor stimulation
Sammanfattning : The purpose of this study was to investigate the role of protein kinases in peripheral nerve regeneration, with the use of dorsal root ganglia (DRG) and nodose ganglia explants from adult mice. The effects of neurotrophic factor stimulation and protein kinase inhibition were studied for long (days) and short term (minutes) effects. LÄS MER