Sökning: "NATURAL SCIENCES Chemistry Organic chemistry Pharmaceutical chemistry"
Visar resultat 1 - 5 av 40 avhandlingar innehållade orden NATURAL SCIENCES Chemistry Organic chemistry Pharmaceutical chemistry.
1. Pilicides and Curlicides : Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulence
Sammanfattning : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. LÄS MER
2. On the Versatility of Microwave-Assisted Chemistry : Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry
Sammanfattning : Today, the demand for speed in drug discovery is constantly increasing, particularly in the iterative processes of hit validation and expansion and lead optimization. Irradiation with microwaves (MWs) has been applied in the area of organic synthesis to accelerate chemical reactions and to facilitate the generation of new chemical entities since 1986. LÄS MER
3. Additive-Driven Improvements in Interfacial Properties and Processing of TMP-Polymer Composites
Sammanfattning : Efforts to address environmental concerns have resulted in new regulations designed to plan the reduction of plastic and synthetic polymer usage, necessitating the search for sustainable natural alternatives with comparable cost-effectiveness and mechanical performance. Thermomechanical pulp (TMP) fibres are one of the most affordable natural fibres that have no chemical refining in production, production have a high yield of 90-98% and TMP fibres have been demonstrated to improve the mechanical characteristics (strength, stiffness and toughness) of wood-polymer composites (WPCs) compared to the pure polymer. LÄS MER
4. Crystallization of Parabens : Thermodynamics, Nucleation and Processing
Sammanfattning : In this work, the solubility of butyl paraben in 7 pure solvents and in 5 different ethanol-water mixtures has been determined from 1 ˚C to 50 ˚C. The solubility of ethyl paraben and propyl paraben in various solvents has been determined at 10 ˚C. LÄS MER
5. Investigating polymorphism in small molecules using three-dimensional electron diffraction
Sammanfattning : For scientific, regulatory and intellectual property reasons, the discovery and characterisation of polymorphic systems is an integral aspect of the development process of any solid-formulated drug product. Yet, these studies are often hindered by crystal quality and size, poor yields and the generation of mixtures of phases. LÄS MER