Sökning: "Mouse strains"

Visar resultat 1 - 5 av 161 avhandlingar innehållade orden Mouse strains.

  1. 1. Automated behavioral phenotyping of inbred mouse strains and mouse models of Alzheimer disease

    Författare :Alina Codita; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Behavioral characterization of various mouse strains created as models for human diseases such as Alzheimer disease requires robust phenotyping methods. Previous work on inbred mouse strains has shown that some of the widely used behavioral methods yield inconsistent results across laboratories, in spite of standardization efforts. LÄS MER

  3. 2. Plasticity in mice nociceptive spinal circuits -role of cell adhesion molecules

    Författare :Jonas Thelin; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long term-potentiation; Cell adhesion molecule; Pain; Somatosensory imprinting; Medicin människa och djur ; Medicine human and vertebrates ; Nociceptive withdrawal reflex; Species differences; Central sensitisation; Mouse strains; Spinal cord;

    Sammanfattning : Introduction: To understand the function of the genes and their products in the pain system, studies will have to deal with complex issues related to intercellular communication, e.g. plasticity in neuronal networks. LÄS MER

  4. 3. Gastric and enteric Helicobacter species in animal models and in the human colon

    Författare :Erik Sturegård; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; Mikrobiologi; bakteriologi; IL-10; Microbiology; bacteriology; virology; virologi; mykologi; hepatitis; colitis; IBD; inflammatory bowel disease; gastritis; animal model; mouse; guinea pig; Helicobacter ganmani; Helicobacter; Helicobacter pylori;

    Sammanfattning : The Gram-negative genus of Helicobacter consists of many bacterial species that colonize a wide range of animal hosts. The genus can be divided into gastric species that colonize the stomach, and enteric species that preferentially colonize the colon and biliary tree of various animal hosts. LÄS MER

  5. 4. Susceptibility to Acute Decompensated Heart Failure in Two Common Mouse Strains

    Författare :Mediha Becriovic-Agic; Michael Hultström; Lena Jonasson; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : Heart failure is a clinical syndrome characterized by an inability of the heart to meet oxygen demands of the body. During the initial stage of heart failure development compensatory mechanisms are activated to help the heart sustain proper function. Over time these compensatory mechanisms become inadequate resulting in decompensation. LÄS MER

  7. 5. Functional studies of candidate genes contributing to type 1 diabetes in the NOD mouse

    Författare :Marie Lundholm; Dan Holmberg; Vivianne Malmström; Umeå universitet; []
    Nyckelord :Type 1 Diabetes; NOD mouse; CTLA-4; Ctex; CD3ζ; apoptosis; Idd6; Lrmp; medicinsk genetik; Medical Genetics;

    Sammanfattning : Type 1 Diabetes (T1D) is an autoimmune disorder caused by both genetic and environmental factors. The non-obese diabetic (NOD) mouse is one of the best and most commonly studied animal models for T1D. This mouse strain spontaneously develops diabetes through a process that closely resembles the human pathogenesis. LÄS MER