Sökning: "Monica Wiig"

Hittade 3 avhandlingar innehållade orden Monica Wiig.

  1. 1. Biomolecular Aspects of Flexor Tendon Healing

    Författare :Maria Berglund; Monica Wiig; Olof Nilsson; Jan Fridén; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Flexor tendon healing; Growth factor; Metalloproteinase; Collagen; Proteoglycan; Myofibroblast; Hyaluronan synthase; Mast cell; Hand surgery; Handkirurgi; Orthopaedics; Ortopedi;

    Sammanfattning : Flexor tendon injuries in zone II of the hand (i.e. between the distal volar crease and the distal interphalangeal joint) can be costly for both the afflicted individual and society because of the high cost of a long rehabilitation period, complicated by tendon ruptures or scarring with adhesion formation, causing impaired range of motion. LÄS MER

  3. 2. Intrasynovial flexor tendon injuries and repair

    Författare :Sara Edsfeldt; Monica Wiig; Kenneth Jonsson; Lars Adolfsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Complications after surgical repair of intrasynovial flexor tendon injuries in the hand occur despite advanced suture techniques and structured postoperative rehabilitation regimens. Early controlled tendon mobilization prevents adhesion formations and improves tendon healing as well as digit range of motion. LÄS MER

  4. 3. Bone Enhancement with BMP-2 for Safe Clinical Translation

    Författare :Marta Kisiel; Jöns Hilborn; Monica Wiig; Richard Oreffo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bone repair; Bone healing; Bone morhogenetic protein-2; Osteogenesis; Extracelular matrix; Hyaluronan; Animal model; Orthopaedics; Ortopedi; Engineering Science with specialization in Materials Science; Teknisk fysik med inriktning mot materialvetenskap;

    Sammanfattning : Bone morphogenetic protein-2 (BMP-2) is considered a promising adjuvant for the treatment of bone regeneration. However, BMP-2 delivery in a conventional collagen scaffold needs a high dose to achieve an effective outcome. Moreover, such dosage may lead to serious side effects. LÄS MER