Sökning: "Medicine human and vertebrates"

Visar resultat 21 - 25 av 198 avhandlingar innehållade orden Medicine human and vertebrates.

1. 21. Women, smoking and myocardial infarction

   Författare :Ellis Janzon; Kardiovaskulär forskning - epidemiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epidemiology; Medicine human and vertebrates ; Smoking cessation; Smoking; risk; Prevention; Trends; Myocardial infarction; Women; epidemiologi; Folkhälsa; Public health; Medicin människa och djur ; Blood pressure; Women;

   Sammanfattning : The aim of this thesis has been to explore factors associated with smoking and smoking cessation in women and the relation between smoking and incidence of myocardial infarction (MI). The time trends in incidence of MI 1986-2002 in the city of Malmö (pop. 250.000) were explored. LÄS MER

3. 22. Characterization of human myeloid progenitors and their differentiation

   Författare :Louise Edvardsson; Avdelningen för hematologi och transfusionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; extracellular fluids; Haematology; Medicin människa och djur ; thrombopoietin receptor; hematopoiesis; transcription factors; growth factor receptors; human myeloid progenitors; Hematologi; extracellulära vätskor;

   Sammanfattning : All hematopoietic cells are derived from the hematopoietic stem cells (HSCs) in a continuous and dynamic process, regulated by a network of transcription factors in different combinations and extrinsic signals from growth factors (GFs) and other factors in the microenvironment. In the initial stages of hematopoiesis HSCs differentiate to progenitor cells with gradually more restricted lineage potential and according to the most accepted model the first restriction in developmental potential results in commitment to either the lymphoid or the myeloid branch, in the latter followed by commitment to the neutrophil/monocyte and erythrocyte/megakaryocyte lineages. LÄS MER

4. 23. Mechanisms behind the lipid-lowering effects of ACTH - Studies in different experimental models

   Författare :Maria Skoog; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Lipid; ACTH; Apolipoprotein-B; Cholesterol; Human; Rat; Rabbit; Medicin människa och djur ;

   Sammanfattning : Abstract Adrenocorticotrophic hormone (ACTH) has strong and direct lipid-lowering effects in man. All apoB-containing lipoproteins, i.e. VLDL, LDL, Lp(a), are reduced by 25-30%. LÄS MER

5. 24. Aspects of chronic autoimmune thyroiditis in children and adolescents

   Författare :Johan Svensson; Pediatrisk endokrinologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescents; thyroid autoantibodies; enterovirus infection; thyroid ultrasonography; reference standard; goiter; chronic autoimmune thyroiditis; levothyroxine treatment; Medicin människa och djur ; Medicine human and vertebrates ; children;

   Sammanfattning : The aims of this thesis were to 1) compare different methods for detection of antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb), particulary in children with chronic autoimmune thyroditis (AIT), 2) investigate if maternal enterovirus infection is a risk factor for development of AIT in offspring, 3) ascertain the prevalence of thyroid autoantibodies in cord blood sera from children who later developed AIT, 4) develop a new reference standard for interpretation of normative thyroid volumes in Swedish children, and 5) evaluate the effect of Levothyroxine (L-thyroxine) treatment on thyroid size in children and adolescents with AIT. We found that 1) Methods based on radioimmunoassay (RIA) were more efficient in detecting both TgAb and TPOAb in children with AIT than methods based on agglutination. LÄS MER

7. 25. Heritability of blood pressure: monogenes and polygenes

   Författare :Cristiano Fava; diabetes och endokrinologi Genomik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Biomedicinska vetenskaper; Biomedical sciences; kidney; Adducin-1; CLC-kb; Gitelman syndrome; association; heritabilty; genetics; hypertension; Blood pressure; blood pressure variability; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : High blood pressure (BP) is associated with cardiovascular morbidity and mortality. Both genetic and environmental factors are implicated in BP homeostatsis and hypertension development. LÄS MER