Sökning: "Maria Tenje"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Maria Tenje.
1. Micropatterning of hyaluronic acid hydrogels for in vitro models
Sammanfattning : The human body consist of a vast number of cells, and jointly, the cells, form tissues and organs. The cells interact and respond to their local microenvironment. LÄS MER
2. Chemical micropatterning of hyaluronic acid hydrogels for brain endothelial in vitro cell studies
Sammanfattning : The building blocks of human tissues are cells. The cells interact and respond to the characteristics of their local microenvironment. The cellular microenvironment is formed by three main components, the extracellular matrix, neighbouring cells and signalling molecules. LÄS MER
3. Fabrication of cantilever chip with complementary micro channel system in SU-8 for biochemical detection
Sammanfattning : This thesis presents the works on fabrication and measurements done with micro cantilevers and a micro channel system, fabricated in the photo-resist SU-8. SU-8 is a polymer patterned by UV lithography which offers a cheap and fast processing and is an interesting alternative to standard Si techniques. LÄS MER
4. Utilizing Biopolymers in 3D Tumor Modeling and Tumor Diagnosis
Sammanfattning : Cancer represents a significant global public health challenge and ranks as the second mostcommon cause of death in the United States. The onset of cancer entails an initial phasewhere cells lose their polarity and disconnect from the normal basement membrane, allowingthem to form distinct three-dimensional (3D) configurations that interact with adjacent cellsand the surrounding microenvironment. LÄS MER
5. Fabrication advances of microvasculature models on-chip
Sammanfattning : Despite the technological advances of the last decades, drug development remains a lengthy and costly process with uncertainties still associated with the poor predictive power of the in vitro and animal models. To address this limitation, microphysiological systems have been introduced in an attempt to increase the biological relevance of in vitro devices. LÄS MER