Sökning: "Malassezia"

Visar resultat 6 - 10 av 10 avhandlingar innehållade ordet Malassezia.

  1. 6. Identification and characterization of allergen components of the opportunistic yeast Malassezia furfur

    Författare :Arezou Zargari; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :allergen; atopic dermatitis; baculovirus; Candida albicans; CAP RAST; cDNA; confocal laser scanning microscopy; Escherichia coli; IgE; Malassezia furfur; monoclonal antibody; Pityrosporum orbiculare; recombinant allergen; yeast.;

    Sammanfattning : The yeast Malassezia furfur (Pityrosporum orbiculare) is a member of the human normal skin microflora. It has been suggested that this yeast plays an important role in the pathogenesis of atopic dermatitis (AD). In 40-65% of patients with AD anti-M. furfur activity has been shown with skin tests and/or specific IgE serology. LÄS MER

  3. 7. The role of Malassezia allergens and mast cells in atopic eczema

    Författare :Christine Selander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atopic eczema (AE) is a chronic inflammatory skin disease, characterized by intense itching, dry skin, infiltration of immune cells and skin lesions. To date, the cause of AE, a disease affecting 15-30% of children and 2-10% of adults, remains unknown and the pathomechanisms are not fully understood. LÄS MER

  4. 8. Activation of human dendritic cells : role of the allergenic yeast Malassezia and NK cells

    Författare :Eva Buentke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Antigen-presenting cells; atopic eczema dermatitis syndrome; cytokines; dendritic cells; Malassezia; NK cells; yeast;

    Sammanfattning : Immature bone marrow derived dendritic cells (DCs) patrol the periphery of our body, where they encounter and take up foreign antigens. Once activated, DCs migrate to regional lymph nodes to present peptides derived from these antigens to naive T cells, and elicit different T helper (Th) cell responses. LÄS MER

  5. 9. Gene expression and genetic association studies in eczema

    Författare :Agne Liedén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Eczema is an itching relapsing and often chronic inflammatory skin disorder associated with cutaneous hyper reactivity to environmental triggers that are innocuous to normal individuals. The differentiation of epidermal keratinocytes leads to the formation of a physical barrier and together with appropriate innate immune responses produce a functional epidermal barrier protecting us against a number of detrimental factors in the external environment. LÄS MER

  7. 10. Exosomes : the future of vaccination?

    Författare :Ulf Gehrmann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Exosomes are small membrane vesicles that are secreted by cells as means of intercellular communication. They are typically between 50 and 100 nm in diameter and originate from the endosomal compartment of cells. Exosomes have been considered a potential novel cell- free therapeutic agent since exosomes are capable of antigen presentation. LÄS MER