Sökning: "MTERF3"

Hittade 3 avhandlingar innehållade ordet MTERF3.

1. 1. Molecular mechanisms of mammalian mitochondrial DNA replication and transcription

   Författare :Mina Pellegrini; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mitochondrion; DNA polymerase gamma; mtSSB; TWINKLE; DNA replication; transcription; mTERF; MTERF3; MTERF2; nucleoid;

   Sammanfattning : Mitochondria are cytoplasmic organelles in eukaryotic cells, mainly devoted to the synthesis of ATP, through the Oxydative Phospshorylation System (OXPHOS). The organelle has its own genome, the mitochondrial DNA (mtDNA) that encodes for all the RNA components of the mitochondrial translation apparatus (two rRNAs and 22 tRNAs) and for 13 subunits of the OXPHOS complexes. LÄS MER

3. 2. Regulation of mitochondrial gene expression in metazoa

   Författare :Ana Bratic; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Drosophila melanogaster; ;

   Sammanfattning : Mitochondria are essential organelles of eukaryotic cells and their main function is to provide the cell with the ubiquitously used energy currency ATP. Impaired energy conversion caused by mitochondrial dysfunction is a direct cause of several human diseases. LÄS MER

4. 3. Mitochondria, contractility and Ca2+ handling : cardiac and skeletal muscle adaptations in health and disease

   Författare :Daniel C Andersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Contractility is a fundamental feature of skeletal and cardiac muscles. An indispensable step in the cellular signal for contraction is a transient elevation in cytoplasmic free [Ca2+] ([Ca2+]i). Both the production of contractile force and Ca2+ handling processes are highly energy demanding. LÄS MER