Sökning: "MSI"
Visar resultat 1 - 5 av 79 avhandlingar innehållade ordet MSI.
1. Genetic and epidemiological studies of hereditary colorectal cancer
Sammanfattning : Lynch syndrome (Hereditary Nonpolyposis Colorectal Cancer, HNPCC) is the most common hereditary syndrome predisposing to colorectal cancer, accounting for 1-3% of all colorectal cancer. This multi-organ cancer predisposition syndrome is caused by mutations in the mismatch repair (MMR) genes, especially MLH1 and MSH2, and to lesser extents MSH6 and PMS2, which lead to widespread genetic instability and thus microsatellite instability (MSI). LÄS MER
2. Associations of sex, anthropometric and reproductive factors with clinicopathological and molecular characteristics of colorectal cancer
Sammanfattning : Colorectal cancer (CRC) is the third most common cancer globally, with approximately 1.2 million new cases every year. The highest incidence rates are seen in developed countries, thereby imposing dietary and lifestyle factors in the etiology of CRC. LÄS MER
3. Metabolic Risk Factors and Molecular Subtypes of Colorectal Cancer
Sammanfattning : Background: Colorectal cancer (CRC) is a heterogeneous disease developing from distinct pathways, resulting in tumor subtypes with large differences in clinical and molecular characteristics. Molecular characteristics are increasingly being used clinically to guide therapy. LÄS MER
4. Applications of nanospray desorption electrospray ionization mass spectrome : Analysis of lipids and metabolites in brain tissue sections and single cells
Sammanfattning : .... LÄS MER
5. Orthodontic anchorage with miniscrews : towards new possibilities
Sammanfattning : .... LÄS MER