Sökning: "MMCT microcell mediated chromosome transfer"

Hittade 1 avhandling innehållade orden MMCT microcell mediated chromosome transfer.

1. 1. Identification of the common eliminated region (CER1) by the microcell hybrid based 'elimination test'

   Författare :Ying Yang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Elimination test; common eliminated region 1 CER1 ; 3p21.3; microcell hybrids; tumor suppressor gene; LF lactoferrin ; LIMD1 LIM-domain containing gene 1 ; sequencing; MMCT microcell mediated chromosome transfer ; real time PM methylation;

   Sammanfattning : The aim of elimination test (Et) is to identify tumor antagonizing genes from chromosome regions that are regularly deleted in microcell hybrid (MCH) derived tumors through serial SCID mice passages. Et so far was focused on the short arm of human chromosome 3 (chr 3) due to its frequent deletions in 21 tumor types including renal cell carcinoma (RCC), small cell lung carcinoma (SCLC) and breast cancer (BRC). LÄS MER