Sökning: "MG subgroups"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden MG subgroups.

  1. 1. Environmental Factors of Importance in Myasthenia Gravis : Emphasis on Physical Activity

    Författare :Elisabet Westerberg; Anna Rostedt Punga; Anne-Marie Landtblom; Chantal Tallaksen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Myasthenia Gravis; MG subgroups; Environmental factors; Lifestyle; Physical activity; Exercise; Clinical Neurophysiology; Klinisk neurofysiologi;

    Sammanfattning : Myasthenia Gravis (MG) is an autoimmune disease caused by antibodies directed against proteins at the neuromuscular junction (NMJ). The disturbed neuromuscular transmission induces fatigable weakness in skeletal muscles. LÄS MER

  3. 2. Cardiovascular effects of short-term exposure to air pollution : exploring potential pathways and susceptible subgroups

    Författare :Petter Ljungman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cardiovascular disease is the most common cause of mortality globally, with a number of contributing risk factors. Ambient air pollution represents a universally present risk factor with a substantial preventive potential. LÄS MER

  4. 3. Genetic and immunological control of human myasthenia gravis

    Författare :Xiaoyan Zhao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Myasthenia Gravis MG ; beta2-adrenergic receptor beta2-AR ; CCR2; CCR5; cytolytic T lymphocyte-associated antigen-4 CTLA-4 ; OX40;

    Sammanfattning : Myasthenia gravis (MG) is a classical autoimmune disease characterized by muscle weakness due to an immune attack against the nicotinic acetylcholine receptor (AChR) on the post-synaptic membrane of the neuromuscular junction. Because of the involvement of multiple factors in the disease, the overall aims of this thesis were to uncover the regulation of candidate genes and the possible cellular mechanisms involved in the immuno-regulation of human MG. LÄS MER

  5. 4. New Biomarkers for Neuromuscular Function and Myasthenia Gravis

    Författare :Carl Johan Molin; Anna Rostedt Punga; Johan Widenfalk; Nils Hailer; Jan Verschuuren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; myasthenia gravis; neuromuscular function; neurophysiology;

    Sammanfattning : Myasthenia gravis (MG) is an autoimmune disorder, which is caused by autoantibodies against the acetylcholine receptor (AChR). The cardinal symptom is muscle fatigue, which can range from slight weakness of the extraocular muscles (causing droopy eyelids or double vision), to paralysis of the respiratory muscles. LÄS MER

  7. 5. Genetic factors predisposing to myasthenia gravis and related autoimmune disorders

    Författare :Ryan Ramanujam; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Myasthenia gravis (MG) is an autoimmune disorder in which patients experience weakness of the skeletal or ocular-bulbar muscles. In most patients, anti-AChR antibodies affect the signal across the neuromuscular junction necessary for muscular contraction. LÄS MER