Sökning: "MEDICINE Dermatology and venerology"

Visar resultat 11 - 15 av 94 avhandlingar innehållade orden MEDICINE Dermatology and venerology.

  1. 11. Disease-causing Keratin Mutations and Cytoskeletal Dysfunction in Human Skin : In vitro Models and new Pharmacologic Strategies for Treating Epidermolytic Genodermatoses

    Författare :Jean Christopher Chamcheu; Anders Vahlquist; Hans Törmä; Harshad Navsaria; Marie Virtanen; Torbjörn Egelrud; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epidermolysis bullosa simplex; epidermolytic ichthyosis; genodermatoses; keratin; keratin mutation; keratinocytes; gene therapy; pharmacological therapy; immortalization; gene regulation; trimethylamine N-oxide TMAO ; sodium 4-phenylbutyrate 4-PBA ; tissue engineering; cell culture; heat shock proteins; MAP kinases; Dermatology and venerology; Dermatologi och venerologi; Dermatologi och venereologi; Dermatology and Venerology;

    Sammanfattning : Epidermolysis bullosa simplex (EBS) and epidermolytic ichthyosis (EI) are rare skin fragility diseases characterized by intra-epidermal blistering due to autosomal dominant-negative mutations in basal (KRT5 or KRT14) and suprabasal (KRT1 or KRT10) keratin genes,  respectively. Despite vast knowledge in the disease pathogenesis, the pathomechanisms are not fully understood, and no effective remedies exist. LÄS MER

  3. 12. Ventricular Long Axis Function: Amplitudes and Timings : Echocardiographic Studies in Health and Disease

    Författare :Frederick Bukachi; Anders Waldenstrom; Derek Gibson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Echocardiography; Doppler Tissue Imaging; Ageing; coronary disease; left ventricular function; atrial contraction; electromechanical function; coronary angioplasty.; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; kardiologi; Cardiology;

    Sammanfattning : Background: The ageing process not only increases the risk of coronary artery disease (CAD) but also complicates its diagnosis and treatment. It is therefore important to understand the newer concepts of cardiovascular ageing physiology as well as methods of predicting the outcomes of therapeutic options available for the elderly with severe CAD. LÄS MER

  4. 13. The Emergency Contraceptive Pill – a Second Chance : Knowledge, Attitudes and Experiences Among Users and Providers

    Författare :Gunilla Aneblom; Tanja Tydén; Karin Eurenius; Kristina Gemzell-Danielsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; focus-group; emergency contraception; attitudes; induced abortion; OTC; content analysis; pharmacy; nurse-midwives; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicin; Medicine;

    Sammanfattning : The overall aim of this thesis was to study knowledge, attitudes and experience of emergency contraceptive pills among women and providers. Both quantitative and qualitative methods were used. Focus-group interviews were conducted with teenage-girls (I) and with women who had purchased ECP without prescription (IV). LÄS MER

  5. 14. A Palliative Approach to Dementia Care : Leadership and organisation, existential issues and family support

    Författare :Lars Albinsson; Britt-Marie Ternestedt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Dementia; palliative care; leadership; staff; existential issues; family support; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; hälso- och sjukvårdsforskning; hälso- och sjukvårdsforskning;

    Sammanfattning : The main purpose of this thesis was to apply the WHO and NHS palliative care approach to dementia care. Thirty-one staff-members in mid-Sweden (studies I and II) and 20 next-of- kin (study IV) were interviewed. LÄS MER

  7. 15. External Fixation of Femoral Fractures in Children : Clinical, radiological and functional outcome and cost analysis

    Författare :Hanne Hedin; Lars Engesäter; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Femoral fractures; children; external fixation; overgrowth; malunion; isokinetic muscle strength; cost analysis; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Orthopaedics; ortopedi;

    Sammanfattning : The overall aim of this thesis was to evaluate the outcome when treating children for displaced femoral fractures with external fixation.In a consecutive and prospective study during the period 1993-2000, 96 children aged 3-15 years with 98 displaced femoral fractures were treated with external fixation and early mobilisation. The mean age was 8. LÄS MER