Sökning: "Lysozyme"

Visar resultat 1 - 5 av 70 avhandlingar innehållade ordet Lysozyme.

  1. 1. Unveiling biomacromolecule interactions-NMR and optical spectroscopy studies on ligand binding to DNA and lysozyme

    Detta är en avhandling från Chalmers University of Technology

    Författare :Lisha Wu; Chalmers tekniska högskola.; Chalmers University of Technology.; [2013]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR; CD; fluorescence; DNA; ruthenium compounds; Hoechst 33258; lysozyme; intercalation; structure rearrangements.;

    Sammanfattning : Studies on intercalation of bulky binuclear ruthenium compounds into DNA have attracted attention due to their slow dissociation rate and sequence selectivity. Previous results showed that dumb-bell shaped molecules of the type [μ-(bidppz)(L)4Ru2]4+, L=phenanthroline or bipyridine, bind rapidly on the surface of DNA prior to intercalation. LÄS MER

  2. 2. Amyloid-β and lysozyme proteotoxicity in Drosophila Beneficial effects of lysozyme and serum amyloid P component in models of Alzheimer’s disease and lysozyme amyloidosis

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Liza Bergkvist; Linköpings universitet.; Linköpings universitet.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : In the work presented this thesis, two different conditions that are classified as protein misfolding diseases: Alzheimer's disease and lysozyme amyloidosis and proteins that could have a beneficial effect in these diseases, have been studied using Drosophila melanogaster, commonly known as the fruit fly. The fruit fly has been used for over 100 years to study and better understand fundamental biological processes. LÄS MER

  3. 3. Understanding the dual nature of lysozyme: part villain – part hero A Drosophila melanogaster model of lysozyme amyloidosis

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Linda Helmfors; Linköpings universitet.; Linköpings universitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Amyloid proteins are a distinct class of proteins that can misfold into β-sheet rich structures that later mature to form the characteristic species known as amyloid fibrils, and accumulate in tissues in the human body. The misfolding event is often caused by mutations (or outer factors such as changes in pH) that destabilize the native protein structure. LÄS MER

  4. 4. Lysosomal network proteins as biomarkers and therapeutic targets in neurodegenerative disease

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Andrea Boman; Linköpings universitet.; Linköpings universitet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cerebrospinal fluid CSF ; biomarkers; therapeutic targets; neurodegeneration; Alzheimer’s disease AD ; Parkinson’s disease PD ; Corticobasal degeneration CBD ; Progressive supraneuclear palsy PSP ; Lysosomes; Endosomes; Autophagy; LAMP-2; Lysozyme;

    Sammanfattning : The pre-symptomatic stage of neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) occurs several decades before the clinical onset. Changes in the lysosomal network, i.e. the autophagosomal, endosomal and lysosomal vesicular system, are among the first alterations observed. LÄS MER

  5. 5. Poly (3-hydroxybutyrate) from a moderate halophile: production and modification for new applications

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Marlene Munoz; Lunds universitet.; Lund University.; [2011]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biopolymers; polyhydroxyalkanoates; polyhydroxybutyrate; moderate halophile; Halomonas boliviensis; fermentation; recovery; thermally induced phase separation; scaffolds; covalent modification; hydrophobic ion pairing; polyethylenemine; lysozyme.;

    Sammanfattning : Popular Abstract in English Polyhydroxybutyrate (PHB) is a homopolymer belonging to the family of biopolyesters, polyhydroxyalkanoates (PHA) produced by different bacteria and archaea as intracellular granules often under conditions of metabolic stress due to a limited supply of essential nutrients. The properties of the PHAs are similar to those of polyethylene and polypropylene and can hence replace these fossil based polymers in a large variety of applications. LÄS MER