Sökning: "Louise Fornander"
Hittade 4 avhandlingar innehållade orden Louise Fornander.
1. Biophysical studies of DNA binding – by the large filament-forming protein Rad51 and the small minor-groove binder Hoechst 33258
Sammanfattning : Mechanistic insight into the nature of DNA-binding ligands is crucial for both drug development as well as understanding more complex biological reactions that take place in the cell. In this Thesis, two rather different DNA-binding molecules are considered: 1. LÄS MER
2. DNA-Complexes with Drugs and Proteins
Sammanfattning : DNA is fundamental for all living cells; the DNA holds the genetic code, which is more or less the instruction book for how all cells are built and function. Several diseases are also linked to DNA, emerging either from a mutation in our genome, which could result in a malfunctioning protein, or that the transcription of genes is somehow affected by structural changes in the DNA, induced by mutations or DNA binding molecules. LÄS MER
3. Upper Airway Mucosal Inflammation : Proteomic Studies after Exposure to Irritants and Microbial Agents
Sammanfattning : People are, in their daily lives, exposed to a number of airborne foreign compounds that do not normally affect the body. However, depending on the nature of these compounds, dose and duration of exposure, various airway symptoms may arise. LÄS MER
4. Exposure to trichloramine, trihalomethanes and endotoxins : adverse respiratory and ocular effects among Swedish indoor swimming pool workers
Sammanfattning : Indoor swimming pool facilities often use chlorine for pool water disinfection. Chlorine can also contribute to the formation of unwanted disinfection byproducts (DBPs). Trichloramine and trihalomethanes (THMs) are DBPs formed in swimming pool water and swimming pool air causing occupational exposure. LÄS MER
