Sökning: "LTD4"
Visar resultat 16 - 20 av 36 avhandlingar innehållade ordet LTD4.
16. Studies on 15-lipoxygenase in dendritic cells and leukotriene receptors in Hodgkin lymphoma
Sammanfattning : Classical Hodgkin lymphoma (cHL) is histologically characterized by a minority of malignant cells, the so-called Hodgkin-Reed Sternberg (H-RS) cells, surrounded by inflammatory cells such as T lymphocytes, eosinophils, macrophages and mast cells. It is generally believed that various molecules released by the H-RS cells are of major importance in the pathophysiology of cHL. LÄS MER
17. Studies on the regulation and function of lipoxygenases in Hodgkin lymphoma
Sammanfattning : Hodgkin lymphoma (HL) is a unique entity among the lymphomas, with a minority of malignant Hodgkin and Reed-Sternberg (H-RS) cells surrounded by a broad range of infiltrating cells. The infiltration of certain inflammatory cells has been reported to predict prognosis of the disease. LÄS MER
18. Endothelial cell interactions with neutrophils : studies of adhesion and effects of lipoxygenase metabolites and antirheumatic drugs
Sammanfattning : Inflammation is a process of vital importance in the defence and elimination of microorganisms as well as in the repair of the damaged tissue. However, inadequate or excessive inflammation leads to inflammatory diseases such as rheumatoid arthritis. LÄS MER
19. Allergen-induced airway reactions in the pig in vivo : inflammatory mediators as targets for asthma therapy
Sammanfattning : A pig model for studies of allergen-induced airway reactions has previously been developed. These pigs are actively sensitized to Ascaris suum and challenged with this antigen in the airways under anesthesia. LÄS MER
20. Leukotriene C4 synthase : studies on oligomerization and subcellular localization
Sammanfattning : Leukotrienes (LTs) are polyunsaturated fatty acid derivatives formed by oxygenation of arachidonic acid via the 5-lipoxygenase (5-LO) pathway. Upon activation of inflammatory cells 5-LO is translocated to the nuclear envelope where it converts arachidonic acid to the unstable epoxide LTA4. LÄS MER