Sökning: "Kristoffer Peterson"

Hittade 1 avhandling innehållade orden Kristoffer Peterson.

1. 1. Molecular basis for galectin-ligand interactions : Design, synthesis and analysis of ligands

   Författare :Kristoffer Peterson; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Galectin; Structure-based design; Thiodigalactoside; Huisgen 1; 3-dipolar cycloaddition; Protein-ligand binding interactions;

   Sammanfattning : Galectins are a class of β-galactoside-binding proteins that bind glycoconjugates and have been implicated in cancer, regulation of immunity and inflammation. Design and synthesis have achieved highly potent and selective galectin ligands that can inhibit interactions with glycoproteins and have consequent cellular effects. LÄS MER