Sökning: "Krebs cycle"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Krebs cycle.
1. Mitochondrial Energy Metabolism : Kgd4 is a novel subunit of the α-ketoglutarate dehydrogenase complex
Sammanfattning : Mitochondria are essential organelles of eukaryotic cells and are responsible for their energy metabolism. The citric acid cycle, a chain of redox reactions in the mitochondrial matrix, is a central metabolic hub. LÄS MER
2. Prostate Cancer Diagnosis : experimental and Clinical Studies With HRMAS NMR Spectroscopy
Sammanfattning : A few abnormal cells found in a small piece of prostate tissue are most consequential for a man’s future. The prevalence of prostate cancer (PCa) is increasing globally. LÄS MER
3. Metabolomics and flux analysis by mass spectrometry : Investigations of factors associated with insulin secretion and prostate cancer risk
Sammanfattning : Two of the most common diseases associated with the Western lifestyle are type 2 diabetes (T2D) and prostate cancer (PCa). This is in large part due to decreased physical activity, surplus of dietary energy, and an ageing population. LÄS MER
4. Metabolic intervention during blood cardioplegia. Clinical studies in coronary surgery and heart transplantation
Sammanfattning : Myocardial ischemia and injury (infarction) during open heart surgery and heart transplantation is a problem in spite of the fact that it is a safe procedure today. The myocardial substrate metabolism is well investigated before and after the cardioplegic period but little knowledge exists about the myocardial metabolic changes during cardioplegia. LÄS MER
5. Protein phosphorylation cascades regulating islet beta-cell insulin exocytosis through glucose sensing and drug signaling : with special focus on serine/threonine protein phosphates and hypoglycemic sulfonylureas
Sammanfattning : In human type 2 diabetes, loss of glucose-sensitive insulin secretion from the pancreatic �-cell is an early pathogenetic event. Initially, this may be compensated for by stimulating insulin secretion by sulfonylurea drugs. LÄS MER