Sökning: "Klinisk genetik"
Visar resultat 21 - 25 av 433 avhandlingar innehållade orden Klinisk genetik.
21. Genetic analysis of murine malaria
Sammanfattning : Malaria, an infectious disease caused by Plasmodium parasites, is one of the major world-scale health problems. Despite the efforts aimed at finding an effective way to control the disease, the success has been thwarted by the emergence of parasite drug resistance and mosquito resistance to insecticides. LÄS MER
22. Phylogeography of the Adder, Vipera berus
Sammanfattning : The phylogeography of a wide ranging temperate species, the adder, Vipera berus, was investigated using several genetic tools, with special emphasis on the post-glacial colonisation pattern of Fennoscandia. The area was colonised from two directions by adder populations representing different glacial refugia. LÄS MER
23. Genotyping RNA and DNA using padlock probes
Sammanfattning : Novel techniques are needed to investigate the genetic variation revealed in the first draft of the human genome sequence. Padlock probes are recently developed reagents, suitable for detecting single-nucleotide variations of DNA and RNA in situ or in solution. LÄS MER
24. Nuclear Organization of Gene Expression in Adenovirus Infected Cells
Sammanfattning : Adenovirus infected cells provide a good model system for studying nuclear organization during RNA production and transport. This thesis is focused on the dynamic organization of splicing factors during the late phase of Adenovirus infection in HeLa cells, the nuclear localization of viral RNA, and the pathway used for viral RNA transport to the cytoplasm. LÄS MER
25. Genetic studies of two inherited human phenotypes : Hearing loss and monoamine oxidase activity
Sammanfattning : This thesis focuses on the identification of genetic factors underlying two inherited human phenotypes: hearing loss and monoamine oxidase activity. Non-syndromic hearing loss segregating in a Swedish family was tested for linkage to 13 previously reported candidate loci for hearing disabilities. LÄS MER