Sökning: "Kinin"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet Kinin.

  1. 1. Kinin System Activation in Vasculitis

    Författare :Robin Kahn; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kinin receptors; inflammation; vasculitis; proteinase 3; neutophils; anti-neutrophil-cytoplasmic antibodies; Kinin;

    Sammanfattning : The kinin system is activated when high-molecular-weight kininogen (HK) is cleaved by plasma kallikrein thus generating bradykinin. Bradykinin is a potent proinflammatory peptide that induces plasma leakage, blood pressure drop, liberation of inflammatory cytokines and pain. LÄS MER

  3. 2. The kallikrein-kinin system in primary hypertension : dynamics of circulating components of the kallikrein-kinin system in relation to the renin-angiotensin-aldosterone system

    Författare :K. Peter Öhman; Linköpings universitet; []
    Nyckelord :aldosterone; angiotensin Il; blood pressure; human; prekallikrein; renin; tissue kallikrein; MEDICINE; MEDICIN;

    Sammanfattning : Kinins are potent vasodilatory and blood pressure lowering peptides, with additional effects on renal handling of electrolytes and water. The kallikrein-kinin system consists of two separate entities, one confined to the circulation and the other to both tissues and the circulation. LÄS MER

  4. 3. Inflammation, kinins, and kinin receptors

    Författare :Sara Bengtson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Evidence is accumulating that the pathogenesis of many diseases is triggered by inappropriate inflammatory responses. These serious complications may occur when the tightly regulated inflammatory network is out of balance and it is now clear that this can eventually cause substantial harm to own cells and tissues. LÄS MER

  5. 4. Studies on the fibrinolytic and kallikrein-kinin systems with special reference to thromboembolism : experimental, clinical and autopsy investigations

    Författare :Mats Eriksson; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  7. 5. Tissue kallikrein: pathophysiological role in acute pancreatitis

    Författare :Mats Bläckberg; Helsingborg Kliniska Vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute pancreatitis; aprotinin; alpha-macroglobulin; alpha1-proteinase inhibitor; turn over; kinin B2 receptor; kallidin; bradykinin; Tissue kallikrein; kallistatin; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Tissue kallikrein releases pharmacollogically highly active kinins from kininogen. Many other enzymes may also release kinins. The aim of the study was to clarify the pathophysiological role of tissue kallikrein in acute pancreatitis. Two sensitive and specific radioimmunoassays for porcine and human tissue kallikrein were developed. LÄS MER