Sökning: "Jakob wikström"

Hittade 2 avhandlingar innehållade orden Jakob wikström.

  1. 1. Mitochondrial form and function in pancreatic β-cells and brown adipocytes

    Författare :Jakob D Wikström; Jan Nedergaard; Roberta Gottlieb; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mitochondria; beta cells; brown adipose tissue; diabetes; obesity; Physiology; Fysiologi; fysiologi; Physiology;

    Sammanfattning : This thesis is focused on the role of mitochondria in pancreatic β-cells and brown adipose tissue (BAT). Two main aspects of mitochondria were explored; mitochondrial functional efficiency and the interrelationship between mitochondrial shape and function. LÄS MER

  3. 2. Identification and clinical evaluation of senescence-associated markers to distinguish melanocytic nevi from melanomas

    Författare :Kyriakos Orfanidis; Ingrid Synnerstad; Jakob Wikström; John Paoli; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; senescence; nevi; melanoma; melanocytes; fibroblasts; ultraviolet UV radiation;

    Sammanfattning : Melanoma is a form of cancer that develops in melanocytes. While it represents only 5% of skin malignancies, it is the most aggressive and lethal. Benign proliferation of these cells form the melanocytic nevi. The definitive diagnosis of melanocytic nevi or melanoma lesions is histopathologic. LÄS MER