Sökning: "JK"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet JK.

1. 1. Characterisation of weak and null phenotypes in the KEL and JK blood group systems

   Författare :Elisabet Sjöberg Wester; Avdelningen för hematologi och transfusionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; null; SNP; Kidd; JK; Blood group; Kell; KEL; weak;

   Sammanfattning : The focus of this thesis is on KEL and JK, two clinically important blood group systems, and the investigations of blood samples with aberrant antigen expression as in null and weak phenotypes, or with a phenotype that does not correspond to genotype. With the increasing use of DNA assays based on single nucleotide polymorphisms for blood group prediction, it is important to characterize the blood-groupencoding genes. LÄS MER

3. 2. Titchmarsh-Weyl M-function asymptotics and some results in the inverse spectral theory for vector-valued Sturm-Liouville equations and a certain higher order ordinary differential equation

   Författare :Erik Andersson; Matematik (naturvetenskapliga fakulteten); []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Functions; differential equations; Funktioner; differentialekvationer; Paley-Wiener.; The generalized Fourier transform; A certain higher order ordinary differential equation; Borg-Marchenko theorems; Vector-valued Sturm-Liouville equations; Inverse spectral theory; Titchmarsh-Weyl M-function asymptotics; Asymptotics of solutions; Spectral measure;

   Sammanfattning : This discourse is constituted by two separate reprots, where the first one offers an elementary deduction of the leading order term asymptotics for the Titchmarsh-Weyl M-function corresponding to a vector-valued Sturm-Liouville equation of the form -(PU')'+QU=zu, xin[0,b), with P^{-1},W,Q being hermitean with locally integrable entries; and under some additional conditions on P^{-1} and W. In the special case of P=W=I, we give some further asymptotic results for the same M-function. LÄS MER

4. 3. Correlation Between Phenotype and Genotype in Some Clinically Important Blood group Systems

   Författare :Nidal Irshaid; Avdelningen för hematologi och transfusionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; transplantation; serology; transfusion medicine; Blood group; DNA; Immunology; genomic typing; serologi;

   Sammanfattning : In the past decade, the molecular basis for most of the blood group systems has been investigated intensively. Many blood group genes have been cloned and the polymorphisms of clinically significant blood group systems have been elucidated. LÄS MER

5. 4. Plantaricins as a novel group of antibacterial compounds and enhancers of antibiotics

   Författare :Amani Musa; Hazem Khalaf; Torbjörn Bengtsson; Elena Vikström; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacteriocin; antimicrobial peptide; plantaricin; antibiotic resistance; PLNC8 αβ; ESKAPE pathogens;

   Sammanfattning : Antibiotics have revolutionized medicine, however, the rapid development of an-tibiotic resistance among bacteria is diminishing their efficacy. Antimicrobial pep-tides produced by Lactobacillus plantarum, i.e., plantaricins, are considered prom-ising alternatives to antibiotics against infections. LÄS MER

7. 5. Notch signalling in carcinogenesis : With special emphasis on T-cell lymphoma and colorectal cancer

   Författare :Jonas Ungerbäck; Peter Söderkvist; Ola Hermanson; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Notch signalling; T-cell lymphoma; colorectal cancer; Wnt signalling; transcription; Medical cell biology; Medicinsk cellbiologi;

   Sammanfattning : The Notch signalling pathway is an evolutionary conserved pathway, named after the Notch receptors, Notch1-4 in mammals, which upon cell-cell contact and ligand binding releases the intracellular domain (NICD). NICD translocates into the nucleus where it binds the transcriptional repressor RBP-Jk, which together with co-activators belonging to the Mastermind-like family of proteins form a transcriptional activation complex. LÄS MER