Sökning: "Invasin"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet Invasin.

  1. 1. Effects of invasin and YopH of Yersinia pseudotuberculosis on host cell signaling

    Författare :Anna Gustavsson; Maria Fällman; Arnoud Sonnenberg; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; β1-integrin; Yersinia pseudotuberculosis; Invasin; YopH; Cell-Matrix Adhesion; Filopodia; Cell Spreading; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Integrins are a large family of membrane-spanning heterodimeric (αβ) receptors that bind to ligands on other cells or to extracellular matrix (ECM) proteins. These receptors mediate bidirectional signaling over the cell membrane to induce signaling cascades mediating functions as cell adhesion, spreading and migration. LÄS MER

  3. 2. Controlling virulence in Yersinia pseudotuberculosis through accumulation of phosphorylated CpxR

    Författare :Edvin Thanikkal; Matthew Francis; Andrew Darwin; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Y. pseudotuberculosis; CpxA; CpxR; invasin; RovA; RovM; T3SS; virulence; transcriptional regulation; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Sammanfattning : Like many Gram-negative bacteria, the food-borne pathogen Yersinia pseudotuberculosis harbours different regulatory mechanisms to maintain an intact bacterial envelope especially during exposure to extracytoplasmic stress (ECS). The CpxA-CpxR two component regulatory system is one such ECS-responsive regulatory mechanism. LÄS MER

  4. 3. Interactions between Yersinia pseudotuberculosis and host cells - role of invasin and YopH

    Författare :Nivia Hamid; Erik Lundgren; Erik Kihlström; Umeå universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  5. 4. Inhibition of phagocyte signaling by the Yersinia virulence protein YopH

    Författare :Kerstin Andersson; Kerstin Andersson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Yersinia pseudotuberculosis evades the immediate immune defense of a host organism by inhibiting bactericidal functions of phagocytes, including phagocytosis, cytokine release, and the oxidative burst. Consequently, this pathogen can survive and multiply in lymphatic tissues. An ensemble of proteins called Yops are involved in the virulence of Y. LÄS MER

  7. 5. Perturbation of the epithelial barrier by enteric pathogens

    Författare :Farideh Tafazoli; Magnusson Karl-Eric; Hakon Leffler; Linköpings universitet; []
    Nyckelord :enteric pathogens: signal transduction; barrier function; MEDICINE; MEDICIN;

    Sammanfattning : Gastrointestinal infections in humans have been associated with a number of diseased condition, including stomach ulcers, gastroenteritis, Crohn's disease, and rheumatic arthritis. Such infections often cause altered intestinal permeability through perturbation of the tight junctions that hold epithelial cells together. LÄS MER