Sökning: "Interstitial connective tissue"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Interstitial connective tissue.

  1. 1. Integrin αVβ3-Directed Contraction by Connective Tissue Cells : Role in Control of Interstitial Fluid Pressure and Modulation by Bacterial Proteins

    Författare :Åsa Lidén; Kristofer Rubin; Karl-Eric Magnusson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; interstitial fluid pressure; collagen gel contraction; integrin αVβ3; septic shock; fibronectin; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : This thesis aimed at studying mechanisms involved in control of tissue fluid homeostasis during inflammation.The interstitial fluid pressure (PIF) is of importance for control of tissue fluid balance. A lowering of PIF in vivo will result in a transport of fluid from the circulation into the tissue, leading to edema. LÄS MER

  3. 2. Intra- and Extracellular Modulation of Integrin-directed Connective Tissue Cell Contraction

    Författare :Tijs van Wieringen; Kristofer Rubin; Anders Arner; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Interstitial fluid pressure; PDGF-BB; bacterial proteins; αVβ3 integrin; cytoskeleton; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : All blood vessels in the microvasculature are embedded in loose connective tissue, which regulates the transport of fluid to and from tissues. The intersti-tial fluid pressure (IFP) is one of the forces that control this transport. LÄS MER

  4. 3. Fibroblast Contractility in vivo and in vitro : Effects of Prostaglandins and Potential Role for Inner Ear Fluid Homeostasis

    Författare :Anna-Karin Hultgård Ekwall; Kristofer Rubin; Helge Rask-Andersen; Bengt Rippe; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Interstitial connective tissue; fibroblasts; prostaglandins; podoplanin; endolymph resorption; Ménière’s disease.; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : Fibroblasts continuously strive to organize and compact the surrounding extracellular matrix (ECM). Recent data suggest that this cellular contractility controls interstitial fluid homeostasis in loose connective tissues (CT). LÄS MER

  5. 4. Extracellular Matrix and Connective Tissue Cells of the Tumor Microenvironment

    Författare :Tomas Friman; Christian Sundberg; Kristofer Rubin; Ulf Eriksson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Tumour biology; Tumörbiologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : In addition to malignant cells, solid tumors comprise supporting stromal tissue that consists of extra cellular matrix (ECM), connective tissue cells, inflammatory cells and blood vessels. The stromal compartment and the malignant cells together shape the tumor microenvironment that in turn determines tumor progression and efficacy of anti-tumor treatments. LÄS MER

  7. 5. Extracellular Matrix and Actin Cytoskeleton - the Control Unit of Interstitial Fluid Volume

    Författare :Vahid Reyhani; Kristofer Rubin; Markella Ponticos; Uppsala universitet; []
    Nyckelord :Collagen; fibrin; integrins; PDGF-BB; gel contraction; fluid homeostasis; interstitial fluid pressure; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : The regulation of fluid (water) volume in the body is crucial for tissue homeostasis. The interstitial fluid, which comprises almost 20% of the body fluid, is stored in the loose connective tissue and its volume is actively regulated by components of this tissue. LÄS MER