Sökning: "Inflammatory diseases"

Visar resultat 1 - 5 av 830 avhandlingar innehållade orden Inflammatory diseases.

  1. 1. Chronic inflammatory bowel diseases : studies of microbiota and its influence

    Författare :Adam Carstens; Jonas Halfvarson; Lars Engstrand; Johannes Espolin Roksund Hov; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammatory bowel disease; microscopic colitis; Crohn’s disease; ulcerative colitis; microbiota; microbiome; biological treatment;

    Sammanfattning : Introduction: Inflammatory bowel diseases are becoming increasingly common. The underlying mechanisms are not entirely known but the gut microbiota seem to be involved in the pathogenesis. LÄS MER

  3. 2. Implications of Heparan Sulfate and Heparanase in Inflammatory Diseases

    Författare :Andreas Digre; Jin-Ping Li; Lena Kjellén; Liliana Schaefer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparanase; Heparan sulfate; Inflammation; Inflammatory diseases; Autoimmune diseases; Amyloidosis; Reumathoid arthritis; SAA; APP; A beta; Neuroinflammation; Medical Science; Medicinsk vetenskap; Medical Biochemistry; Medicinsk biokemi; Immunologi; Immunology; Neurology; Neurologi;

    Sammanfattning : Heparan sulfate (HS), an unbranched sulfated carbohydrate chain, and the HS-degrading enzyme heparanase play important roles in physiological and pathological processes during all stages of life, from early embryogenesis to ageing. Accumulated information shows that HS and heparanase are involved in inflammatory processes and associated diseases, e. LÄS MER

  4. 3. Cell signaling in inflammatory diseases and development of antiinflammatory drugs

    Författare :Ahmed El Marghani; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell signaling; antiinflammatory drugs; inflammatory diseases; Immunology; Immunologi; NATURAL SCIENCES; NATURVETENSKAP; Biology; Biologi; Immunologi; Immunology;

    Sammanfattning : .... LÄS MER

  5. 4. NO Effect on Inflammatory Reaction in Extracorporeal Circulation : Ex vivo Studies

    Författare :Mika Lahtinen; Jan Borowiec; Per Venge; Vibeke Videm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Cardiac surgery; extracorporeal circulation; inflammatory reaction; NO; degranulation; neutrophil; eosinophil; basophil; complement; contact system; coagulation; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Nitric oxide (NO) is expressed in inflammatory tissues. However, NO effects are controversial in inflammation; NO is described as acting in a dose dependent manner and possess both pro-inflammatory and anti-inflammatory properties. LÄS MER

  7. 5. Macrophages in Crohn's Disease: lnnate immune cellular and molecular mechanisms driving intestinal inflammation and fibrosis

    Författare :Frida Gorreja; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; macrophages; inflammatory macrophages; tissue-resident macrophages; efferocytosis; innate immunity; myeloid cells; fibroblasts; fibrosis; inflammasomes; Crohn´s disease; inflammatory bowel diseases; digestive diseases; mucosa immunology; intestinal immunity; intestinal inflammation; serum systemic inflammation; microbiota; metabolites;

    Sammanfattning : Macrophages and their interactions with the lamina propria and luminal microenvi-ronment are crucial in the pathogenesis of Crohn´s disease (CD), a chronic inflamma-tory disease with a strong inflammatory innate immune involvement. Therefore, in-terpreting macrophage activity in the intestinal microenvironment may identify treatment targets beneficial for at least a subgroup of patients. LÄS MER