Sökning: "IgE-mediated histamine release"

Hittade 3 avhandlingar innehållade orden IgE-mediated histamine release.

  1. 1. Experimental and Clinical Studies of SLPI, with Special Reference to IgE-Mediated Allergic Reactions

    Författare :Ulla Westin; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in situ hybridisation; immunohistochemistry; allergic rhinitis; atopic subjects; IgE-mediated histamine release; mast cell proteases; plasma protease inhibitors; SLPI; human leukocyte proteases; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : In this study we demonstrated the production of SLPI (Secretory Leukocyte Protease Inhibitor) in serous glands in the nasal mucosa. We have shown that the pattern of the expression of mRNA corresponds to the encoded protein. The encoded protein was detected by immunohistochemical methods and mRNA was discovered by in situ hybridisation. LÄS MER

  3. 2. The contribution of eosinophils and mediators in allergic inflammation

    Författare :Annika Roquet; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :allergic inflammation; eosinophils; bronchial hyperresponsiveness; histamine; leukotrienes; antihistamine; leukotriene-antagonist; low-dose challenge;

    Sammanfattning : The aim of the present work was to investigate the development of allergic inflammation. For this purpose human experimental challenge models in skin, nose and bronchi were used as well as pharmacological interventions. A variety of inflammatory cells and mediators have been suggested as important in the pathogenesis of allergic inflammation. LÄS MER

  4. 3. Nitric oxide and eicosanoids : significance and interactions during antigen-induced responses in peripheral lung tissue

    Författare :Anna-Karin Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nitric oxide; leukotrienes; prostaglandins; histamine; ovalbumin; contractions; distal lung; rat; human; guinea pig; precision-cut lung slices; mast cell;

    Sammanfattning : Asthma means difficulty in breathing and is described as a chronic, inflammatory disorder that produces narrowing of the lower respiratory tract. The allergen-induced asthmatic bronchoconstriction is primarily caused by an IgE-mediated release of the mast cell mediators, histamine and eicosanoids (leukotrienes and prostanoids). LÄS MER