Sökning: "IgD-binding"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet IgD-binding.
1. Characterization of IgD-binding by respiratory pathogens
Sammanfattning : The focus of this thesis was to explore the interaction between IgD and Moraxella catarrhalis and Haemophilus influenzae. These two respiratory pathogens are responsible for otitis media in children, and exacerbations in patients afflicted with predisposing conditions such as chronic obstructive pulmonary disease (COPD). Both M. catarrhalis and H. LÄS MER
2. Survival strategies of the human respiratory tract pathogen Haemophilus influenzae
Sammanfattning : Haemophilus influenzae is an important respiratory tract pathogen responsible for a variety of infections in humans. Encapsulated H. influenzae belongs to one of six serotypes (a-f), of which type b is the most virulent one causing serious and sometimes life-threatening diseases (e.g. LÄS MER
3. Identification and Characterization of the Moraxella catarrhalis IgD-binding Protein MID
Sammanfattning : Moraxella catarrhalis is now an established human pathogen that frequently colonizes the upper respiratory tract causing most importantly otitis media in children. It has also been associated with sinusitis, laryngitis and lower respiratory tract infections in adults with predisposing conditions such as chronic obstructive pulmonary disease (COPD). LÄS MER
4. Activation of human B cells with the Moraxella catarrhalis IgD-binding protein MID
Sammanfattning : Moraxella catarrhalis is a respiratory tract pathogen that causes significant health problems, including acute otitis media in children, lower respiratory tract infections in adults and the elderly and sinusitis in both children and adults. The interest in M. LÄS MER
5. Structural characterization of proteins to investigate their roles in diseases: Focus on MID & LTA4H
Sammanfattning : Protein molecules are responsible for many biological functions in cells. In order to fulfill their various biological roles, these chain-like molecules must fold into precise three-dimensional shapes. The knowledge of accurate molecular structures is a prerequisite for rational drug design and for structure based functional studies. LÄS MER