Sökning: "IVIg"

Visar resultat 1 - 5 av 31 avhandlingar innehållade ordet IVIg.

  1. 1. Pathogenesis and immunotherapy of streptococcal septicemia and shock

    Författare :Nahla Ihendyane; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Streptococcus; Cytokines; Superantigens; Sepsis; Inflammation; IVIG;

    Sammanfattning : Streptococei have been recognized as important causes of severe sepsis. Increased frequencies of streptococcal toxic shock syndrome caused by group A streptococcus (GAS) have been noted worldwide during the last 15 years. LÄS MER

  3. 2. Studies of immunopathogenic mechanisms and treatment of chronic, inflammatory myopathies, myositis

    Författare :Maryam Dastmalchi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Idiopathic inflammatory myopathies; polymyositis; dermatomyositis; IVIg; infliximab treatment; physical training; muscle biopsy;

    Sammanfattning : Polymyosit (PM), dermatomyositis (DM) and sporadic inclusion body myositis (sIBM) are chronic inflammatory myopathies which are characterized by muscle weakness, fatigue and extra-muscular involvement. Mononuclear inflammatory cells are typically found in muscle tissue. LÄS MER

  4. 3. Studies in sporadic inclusion body myositis

    Författare :Snjólaug Arnardóttir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord : s-IBM; muscle fibre regeneration; cytoskeleton; IVIg; muscle inflammtion; cytokine; training; sensibility; neuropathy ;

    Sammanfattning : Aims: The general aims of the present study were to increase the understanding of the disease process in s-lBM by analysing the cytoskeletal structure in muscle fibres and their regeneration potential; and also to evaluate sensory function in patients with s-IBM to test the hypothesis of an associated neurogenic component or a concomitant neuropathy in s-IBM; and to evaluate therapeutic options by analysing the effect of IVIg treatment on the muscle inflammation; and to evaluate the effect of training on muscle function and muscle inflammation. Patients: Twenty-six patients with the diagnosis of s41BM participated in these studies. LÄS MER

  5. 4. Immune moldulatory effects of intravenous immunoglobulin in vitro and after allogeneic bone marrow transplantation

    Författare :Sven Klaesson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :IVIG; IgG; F ab 2; Fc; immune modulation; T cell responses; Bcell responses; cytokines; bone marrow transplantation; infections; CMV; graft-versus-hostdisease;

    Sammanfattning : Intravenous immunoglobulin (IVIG) has been used in patients with immunodeficiencies and various autoimmune diseases. Its immune modulatory effect is well documented. In allogeneic bone marrow transplantation (BMT) IVIG has been used to reduce the incidence of infections and graft-versus-host-disease (GVHD). LÄS MER

  7. 5. The role of autoantibodies in inflammatory myopathies

    Författare :Sevim Barbasso Helmers; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Idiopathic inflammatory myopathies; polymyositis; dermatomyositis; inclusion body myositis; ILD; IVIG; IFN; BAFF; endothelial cells; anti-Jo-1;

    Sammanfattning : Polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM), collectively called myositis, are chronic inflammatory myopathies. These disease subsets are heterogeneous but share some features, such as skeletal muscle weakness and inflammatory cell infiltrates in muscle tissue. LÄS MER