Sökning: "IRF1"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet IRF1.

  1. 1. Innate immunity of human intestinal epithelium in childhood celiac disease : influences from celiac disease associated bacteria and dietary oats

    Författare :Grzegorz Pietz; Marie-Louise Hammarström; Thomas T MacDonald; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Celiac disease; dietary oats; gut microbiota; intestinal epithelium; IEL; IFN-γ; IRF1; IL-18; CXC3L1; inflammasome; permeability; Prevotella jejuni; Lachnoanaerobaculum umeaense; immunologi; Immunology;

    Sammanfattning : Background & Aims: Celiac disease (CD) is a chronic inflammatory small-bowel enteropathy caused by permanent intolerance to gliadin in wheat gluten, and related proteins in ray and barley. It is disputed whether CD patients tolerate oats. The only treatment of CD is lifelong gluten-free diet (GFD). LÄS MER

  3. 2. Cytogenetic and Molecular Changes Involving Rat Chromosome 10 in Experimental Endometrial Adenocarcinoma

    Författare :Afrouz Behboudi; Sweden Gothenburg Göteborg University Lundberg Laboratory Department of Cell and Molecular Biology - Genetics; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EAC; rat chromosome 10; RNO10; RH; FISH; tumor suppressor gene; Tp53; Irf1; Tsc2; LOH; AI;

    Sammanfattning : .... LÄS MER

  4. 3. Dissecting the complexity of human susceptibility to Plasmodium falciparum malaria: genetic approaches

    Författare :Valentina D Mangano; Marita Troye-Blomberg; Marta Alarcon; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; genetics; malaria; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : There are many aspects of the immunology of P. falciparum infection that are not understood. Genetic approaches are of great value for dissecting the complexity of immune responses to malaria in natura by providing new insights into molecular interactions between the parasite and the host. LÄS MER

  5. 4. Early life cytokines, viral infections and IgE-mediated allergic disease

    Författare :Anna-Karin Larsson; Marita Troye-Blomberg; Gunnar Lilja; Maria Jenmalm; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; IgE-sensitisation; childhood; cytokine; viral infection; atopy; single nucleotide polymorphism; cord blood; Immunology; Immunologi;

    Sammanfattning : Background: The reasons why some individuals become IgE-sensitised and allergic are largely unknown, though genetic- and early life environmental factors seem to be of importance.Objective: The overall aim of this thesis was to investigate the relationship between IgE-sensitisation and allergic disease, viral infections, genetic markers and early life cytokines. LÄS MER

  7. 5. Human candidate polymorphisms and malaria susceptibility in sympatric ethnic groups, The Fulani and The Dogon of Mali

    Författare :Bakary Maiga; Ann-Kristin Östlund Farrants; Lars Hviid; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malaria; Fulani; Dogon; Blood group; SNPs; IL-4; FcγRIIa; antibody level; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : In malaria endemic regions, resistance to malaria constitutes a critical selective pressureon genetic polymorphisms that regulate immune defense and inflammatory pathways.Differences in malaria susceptibility between sympatric ethnic groups have been described inMali. LÄS MER