Sökning: "Host Cell Proteins"

Visar resultat 1 - 5 av 397 avhandlingar innehållade orden Host Cell Proteins.

  1. 1. Roles of secreted bacterial factors in modulation of host cell signalling

    Författare :Eric Toh; Sun Nyunt Wai; Teresa Frisan; Staffan Bohm; Ann-Beth Jonsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteria-host interaction; motility-associated killing factor A; outer membrane vesicles; cytolysin A; phosphatidylinositol 4-phosphate 5-kinase alpha; enhancer of zeste homologue 2; epigenetic modulation; Medical Cell Biology; medicinsk cellbiologi; mikrobiologi; Microbiology;

    Sammanfattning : Pathogenic bacteria employ several secretion systems to release or inject virulence factors that may alter host cell processes, generate a replicative niche, and aid bacterial survival in adverse environments. This thesis presents my investigations on how bacterial factors can modulate host cell signalling mechanisms. LÄS MER

  3. 2. Studies of Giardia-host interactions: role of cysteine-rich surface proteins

    Författare :Dimitra Peirasmaki; Staffan Svärd; Steven Singer; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Giardia; intestinal parasite; parasite infection; host-parasite interaction; virulence factors; HCMPs; cysteine-rich proteins; secretome; proteome;

    Sammanfattning : Giardia intestinalis is a eukaryotic parasite that colonizes the small intestine of humans and animals causing the diarrheal disease known as giardiasis. This parasite is not invasive and does not internalize into host cells but it rather attaches to the brush border surface of the small intestine disrupting the epithelial barrier. LÄS MER

  4. 3. Tissue reactions to biomaterials

    Författare :Agneta Rosengren; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytochemistry; Histology; Macrophages; Cryosubstitution; Proteins; Immunohistochemistry; Titanium; Implants; PTFE; histochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur;

    Sammanfattning : The biological response to different implanted biomaterials vary. The relative importance of factors in the material and host for this variation are at present incompletely known. LÄS MER

  5. 4. Host cell responses to Helicobacter pylori secreted factors

    Författare :Raquel Garcia Lobato Tavares; Sushil Kumar Pathak; Åsa Sjöling; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; Secreted proteins; Host cell responses; Macrophages; Apoptosis; Pro-inflammatory cytokines; MAPKs; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The infection of the human gastric mucosa by the bacterium Helicobacter pylori can lead to the development of gastritis, gastroduodenal ulcers, and cancer. The factors that determine disease development in a small percentage of infected individuals are still not fully understood. LÄS MER

  7. 5. Antiphagocytosis by Yersinia pseudotuberculosis : role of the YopH target proteins

    Författare :Ming Yuan; Maria Fallman; Tommy Nilsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular biology; Cas; Fyb; mAbp1; SKAP-HOM; Yersinia pseudotuberculosis; YopH; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The enteropathogenic bacterium Yersinia pseudotuberculosis binds to β1 integrins on a host cell via its surface protein invasin. This event stimulates signal transduction to the actin cytoskeleton of the eukaryotic cell, which allows the cell to engulf the bacterium that is attached to its surface. However, the pathogen Y. LÄS MER