Sökning: "High through put screening"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden High through put screening.

1. 1. Primary Recovery of Biologically Active Compounds Using Macroporous Monolithic Hydrogels

   Författare :Amro Hanora; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Downstream processing; macroporous; Biologically active compounds; Biotechnology; Läkemedelsteknik och relaterad teknik; Pharmaceutical and related technologies; Polymerteknik; biopolymers; Biokemisk teknik; Polymer technology; Makromolekylär kemi; Biochemical technology; Affinity chromatography; Ion exchange chromatography; Expanded bed adsorption chromatography.; Macromolecular chemistry; High through put screening; lactica acids; Endotoxin; Plasmid DNA; Cryogel columns; Bioteknik;

   Sammanfattning : The completion of sequencing of human and other mammalian genomes opens a new era for drug development. New approaches have been proposed for tackling diseases such as development of small molecule therapies based on understanding of human genome and proteome, new proteinous based therapies, where the therapeutic protein can inhibit or modify a certain metabolic pathway or DNA-based therapies delivering a gene into the cell (e. LÄS MER

3. 2. Aluminium alloy development for Additive Manufacturing

   Författare :Freddy Leijon; Johan Moverare; Svain Skjervold; Ehsan Ghassemali; Linköpings universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Aluminium alloys; Alloy design; Powder bed fusion; Printability; Solidification cracking; Additive manufacturability; High through put methods; Heterogeneous nucleation;

   Sammanfattning : Powder Bed Fusion (PBF Additive Manufacturing AM have emerged as a promising manufacturing process possessing a powerful combination of characteristics. Most noticeable are the near-net-shape, short lead time and flexibility, both with regard in design freedom and in part-to-part variation. LÄS MER

4. 3. Aspects in bioethics : Theory and practice in a preventive screening for type 1 diabetes

   Författare :Ulrica Gustafsson Stolt; Mats G. Hansson; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : From a clinical perspective, as well as societal and global, the present rapid increase in the number of people diagnosed with diabetes is a cause of great concern. Simultaneously, our understanding of the aetiology and pathogenesis of type 1 diabetes (IDDM) remain limited. LÄS MER

5. 4. Analysis of PDGF receptor internalization and signaling using proximity ligation assays

   Författare :Marie Rubin Sander; Ola Söderberg; Cristina Al-Khalili Szigyarto; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGFRβ; dynamin; proteolytic cleavage; signaling; internalization; protein-protein interaction; short linear motif; viral hijack; in situ PLA; Molboolean;

   Sammanfattning : Cell signaling is mediated by signaling proteins that relay the signal in an intricate network of interactions before the signal is translated into a biological response. Short linear motifs (SLiMs) in intrinsically disordered regions of proteins serve as docking sites for protein interaction in all aspects of cell regulation including signal transduction. LÄS MER

7. 5. Harnessing urinary extracellular vesicles microRNA by acoustic trapping as potential biomarkers for prostate cancer

   Författare :Anson Ku; Avdelningen för translationell cancerforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Prostate cancer (PCa) is an interesting study case of clinical management of uncertainty. PCa is the most diagnosed but only the second-leading cause of non-cutaneous cancer-related mortalities among men in developed countries. To put simply, the life-time risk of PCa diagnosis and mortality is approximately 11% and 3% respectively; a ~3. LÄS MER