Sökning: "HLA B27"

Hittade 3 avhandlingar innehållade orden HLA B27.

  1. 1. Genetic markers in rheumatoid arthritis

    Författare :Solbritt Rantapää Dahlqvist; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; family history; genetic marker; HLA B27; HLA DR4; properdin factor B; C3 complement; -antitrypsin; haptoglobin; transferrin;

    Sammanfattning : Genetic as well as environmental factors are believed to be of importance in the etiology of rheumatoid arthritis (RA). There are a number of previous studies of genetic markers in RA, but so far no genetic linkage and only a few associations have been found. Of the associations only one (with the HLA antigen DR4) appears to be well documented. LÄS MER

  3. 2. A Clinical and Genetic Study of Psoriatic Arthritis

    Författare :Gerd-Marie Alenius; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; Psoriatic arthritis; prevalence; inflammatory manifestations; genetic loci; HLA; TNFB; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; Clinical Genetics; klinisk genetik;

    Sammanfattning : Psoriatic arthritis (PsA) is an inflammatory joint disease associated with psoriasis. PsA has a heterogeneous pattern, expressed by different manifestations such as mild mono-oligoarthritis or very severe, erosive and destructive polyarthritis. Measurable inflammatory activity is not always prominent. LÄS MER

  4. 3. Intestinal permeability : a parameter of mucosal dysfunction

    Författare :Pål Lundin; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Peptide; N-acetylcysteine; Medium-chain glyceride; Mannitol; Macromolecules; Lipid; Kinetics; In vivo; In vitro; In situ; Intestine; Injury; Inflammation; HLA-B27; HCl; Epithelium; Enhancer; dDAVP; 51Cr-EDTA; BSA; Absorption; Albumin; Permeability; Animal physiology; Djurfysiologi;

    Sammanfattning : The gastrointestinal tract has two opposing functions; to absorb nutrients and electrolytes, and to act as a barrier towards hazardous and non-nutritional substances. In the present thesis the barrier function of the gastrointestinal tract was studied in animal models in vivo, in situ and in vitro. LÄS MER