Sökning: "Gunilla Hjerdt-goscinski"

Hittade 1 avhandling innehållade orden Gunilla Hjerdt-goscinski.

1. 1. Antibiotic-induced Bacterial Toxin Release – Inhibition by Protein Synthesis Inhibitors

   Författare :Gunilla Hjerdt-Goscinski; Jan Sjölin; Monica Lundholm; Inga Odenholt; Ingrid Nilsson-Ehle; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Endotoxin; LPS; exotoxin; SpeA; penicillin-binding protein; aminoglycosides; clindamycin; β-lactam antibiotics; severe sepsis; septic shock; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar;

   Sammanfattning : Toxic products, such as endotoxin from the gram-negative and exotoxin from the gram-positive bacteria, are the most important initiators of the inflammatory host response in sepsis. In addition to antibacterial treatment, numerous attempts have been made to interfere with the exaggerated proinflammatory cascade initiated by the toxins. LÄS MER