Sökning: "GotoKakizaki rat"

Hittade 2 avhandlingar innehållade orden GotoKakizaki rat.

  1. 1. Effect of hyperglycemia on glucose transport and intracellular signal transduction in skeletal muscle

    Författare :Yuichi Kawano; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :skeletal muscle; glucose transport; insulin signaling; hyperglycemia; PKC; Akt kinase; GotoKakizaki rat; phlorizin; muscle fiber type;

    Sammanfattning : Recent studies revealing the components of insulin signal transduction have raised the question of whether the defects in insulin signaling account for disturbed glucose metabolism in people with NIDDM. The major focus of this thesis is to elucidate the role of insulin signal transduction in the development of peripheral insulin resistance. LÄS MER

  3. 2. Impact of candidate genes on obesity and type 2 diabetes

    Författare :Ewa-Carin Långberg; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Obesity and type 2 diabetes (T2D) have strong genetic components. Identification of susceptibility genes in both diseases will give better knowledge of their pathomechanisms and future therapies. LÄS MER