Sökning: "Gel-to-Liquid Crystalline Phase Transition"

Hittade 5 avhandlingar innehållade orden Gel-to-Liquid Crystalline Phase Transition.

1. 1. Equilibrium and Kinetic Studies of the Binding of DNA to Cationic Liposomes

   Författare :Paula Barreleiro; Fysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Small-Angle Neutron Scattering; Fluorescence; Kinetics; Stopped-Flow; Differential Scanning Calorimetry; Titration Calorimetry; Gel-to-Liquid Crystalline Phase Transition; Lamellar phase; Lipolexes; DNA; Liposomes; Cryo-TEM; Physical chemistry; Fysikalisk kemi;

   Sammanfattning : The objective of this work was to study the formation of DNA-cationic vesicle complexes (lipoplexes). These complexes are interesting not only from a fundamental point of view but also as promising candidates for gene therapy. The approach taken was to study first the cationic vesicles by themselves. LÄS MER

3. 2. Responding Model Membranes. Lipid Phase Behaviour, Domain Formation and Permeability

   Författare :Emma Sparr; Fysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Water and solute flux; Gradients; Monolayer; Two-dimensional crystals; Line activiy; Osmotic stress; Interlamellar forces; Phospholipid-cholesterol interactions; Phase transitions; Bilayer stack; Stratum corneum; Physical chemistry; Fysikalisk kemi;

   Sammanfattning : This thesis concerns the interplay between the lipid phase behaviour, domain formation and the permeability of bilayer membranes. An essential part of this work has been the understanding of the phase transitions and equilibrium properties of lipid bilayers. LÄS MER

4. 3. Hyperthermia-responsive liposomal systems

   Författare :Yujia Jing; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cationic lipid; asymmetry; phospholipase; liposomes; flip-flop; hyperthermia; phase transition; supported lipid membranes; drug delivery;

   Sammanfattning : Abstract Sophisticated liposomal systems are emerging at an increasing rate to meet the demands for multifunctional drug carriers in chemotherapies in combined with hyperthermia. For example, liposomal drug carriers for temperature-controlled drug release under hyperthermic conditions have recently been tested in clinical trials. LÄS MER

5. 4. Classical and Quantum Descriptions of Proteins, Lipids and Membranes

   Författare :Richard Tjörnhammar; Olle Edholm; Sagar Pandit; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Quantum corrections; Coordination structure; Polarisation; Phase transitions; Kelvin differential equation; Line tension; Elastic membrane models; Molecular particle models; Zinc binding; Cholesterol and Phospholipids; Biological Physics; Biologisk fysik;

   Sammanfattning : In this thesis the properties of proteins and membranes are studied by molecular dynamics simulations. The subject is decomposed into parts addressing free energy calculations in proteins, mechanical inclusion models for lipid bilayers, phase transitions and structural correlations in lipid bilayers and atomistic lipid bilayer models. LÄS MER

7. 5. Physico-Chemical Investigations of Bilayer Discs and Related Lipid Structures Formed in Liposomal Systems Intended for Triggered Release

   Författare :Maria Sandström; Katarina Edwards; Mats Almgren; Tommy Nylander; Uppsala universitet; []
   Nyckelord :Physical chemistry; liposome; triggered release; pH-sensitive liposomes; temperature-sensitive liposomes; drug partitioning; cryo-TEM; discs; Fysikalisk kemi;

   Sammanfattning : This thesis describes results from fundamental studies of liposomes intended for drug delivery and pH or temperature triggered release. In addition, the effect of lipid composition on bilayer disc formation and a potential application of the bilayer discs were investigated. LÄS MER