Sökning: "GLC"

Visar resultat 1 - 5 av 13 avhandlingar innehållade ordet GLC.

  1. 1. Phytosterols. Effect of intake on cholesterol absorption and colorectal cancer risk

    Författare :Lena Normén; Göteborgs universitet; []
    Nyckelord :phytosterols; phytostanols; soy sterols; sitostanol; ester; gas-liquid chromatography; GLC; cholesterol absorption; sterol excretion; fruit; vegetables; cereals; colon cancer; rectal cancer; dietary fiber;

    Sammanfattning : Phytosterols are lipid components of all food items of plant origin. They are effective in decreasing plasma cholesterol concentrations, but have also been suggested to protect against colorectal cancer. LÄS MER

  3. 2. A UDP-glucose deficient mutant cell line as a model to study the cytotoxicity of Clostridium perfringens PLC

    Författare :Marietta Flores Diaz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A Chinese Hamster fibroblast mutant cell line, deficient in UDP-glucose (UDP-Glc) and hypersensitive to Clostridium perfringens phospholipase C (PLC) was used in this study to determine some of the molecular consequences of a cellular UDP-Glc deficiency. Furthermore, using this cell as a model, structure/function studies were performed to identify residues critical for the cytotoxic activity of PLC. LÄS MER

  4. 3. Sucrose cleavage pathways in aspen wood

    Författare :Umut Rende; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Cellulose is the main component of wood and one of the most important renewable raw materials. In several tree species including Populus species, carbon for cellulose biosynthesis is derived from the disaccharide sucrose. LÄS MER

  5. 4. UDP-sugar metabolizing pyrophosphorylases in plants : formation of precursors for essential glycosylation-reactions

    Författare :Daniel Decker; Leszek A. Kleczkowski; Henrik Vibe Schelle; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemical library screening; Cell wall synthesis; Glycosylation; Nucleotide sugars; Oligomerization; Protein structure; Reverse chemical genetics; Sugar activation; UDP-sugar synthesis; biokemisk farmakologi; biochemical pharmacology; biokemi; Biochemistry; biology; biologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : UDP-sugar metabolizing pyrophosphorylases provide the primary mechanism for de novo synthesis of UDP-sugars, which can then be used for myriads of glycosyltranferase reactions, producing cell wall carbohydrates, sucrose, glycoproteins and glycolipids, as well as many other glycosylated compounds. The pyrophosphorylases can be divided into three families: UDP-Glc pyrophosphorylase (UGPase), UDP-sugar pyrophosphorylase (USPase) and UDP-N-acety lglucosamine pyrophosphorylase (UAGPase), which can be discriminated both by differences in accepted substrate range and amino acid sequences. LÄS MER

  7. 5. Glucosyltransferase toxins from clostridia : molecular interactions with cells

    Författare :Esteban Chaves Olarte; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : An enzymatic activity was recently described for the group of Large Clostridial Cytotoxins (LCTs). This activity is glucosyltransfer and consists in the covalent addition of glucose, from UDP-glucose (UDP-Glc) to threonine 35 of small GTPases of the Rho subfamily. LÄS MER