Sökning: "GIY-YIG"

Hittade 2 avhandlingar innehållade ordet GIY-YIG.

1. 1. Endonuclease II - a GIY-YIG enzyme of bacteriophage T4

   Författare :Pernilla Lagerbäck; Karin Carlson; Elisabeth Raleigh; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; GIY-YIG; EndoII; endonuclease; structure; tetramer; binding; nicking; recombination; Microbiology; Mikrobiologi;

   Sammanfattning : Endonuclease II (EndoII) of bacteriophage T4 is a GIY-YIG enzyme involved in host DNA breakdown during phage infection of E. coli. EndoII combines features of restriction endonucleases with those of homing endonucleases in that it breaks down DNA foreign to itself but recognizes a 16 bp long asymmetric and ambiguous sequence. LÄS MER

3. 2. Homing Endonucleases and Horizontal Gene Transfer in Bacteria and Bacteriophages

   Författare :David Nord; Britt-Marie Sjöberg; Steinar Johansen; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; dsDNA cleavage; ribonucleotide reductase; GIY-YIG motif; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

   Sammanfattning : Homing endonuclease genes (HEGs) are selfish genetic elements that mediate their own super-Mendelian inheritance. This is mediated by the homing endonuclease cleavage of a HEG- allele followed by recombination-repair with a HEG+ allele.The majority of the HEGs are encoded in intervening sequences (IVSs). LÄS MER