Sökning: "GFR"

Visar resultat 1 - 5 av 93 avhandlingar innehållade ordet GFR.

  1. 1. Minimizing Risks and Morbidity in Live Kidney Donors

    Författare :Ali-Reza Biglarnia; Jonas Wadström; Gunnar Tufveson; Tomas Lorant; Ingela Fehrman-Ekholm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; live donors; morbidity; GFR; donor nephrectomy; postoperative pain treatment; venous thromboembolism; HARS; Transplantation surgery; Transplantationskirurgi; Medicin; Medicine;

    Sammanfattning : Live kidney donors are healthy volunteers who are exposed to major surgical procedure and physical harms with no direct therapeutic benefits. Efforts to minimize their risks and morbidity are therefore of utmost importance. LÄS MER

  2. 2. Alpha-radioimmunotherapy with At-211: Evaluations and imaging on normal tissues and tumors

    Författare :Tom Bäck; Göteborgs universitet; []
    Nyckelord :radioimmunotherapy; astatine; RBE; renal function; GFR; imaging; targeted radiotherapy; alpha-RIT;

    Sammanfattning : Alpha-radioimmunotherapy (alpha-RIT) is an internal conformal radiotherapy at the cellular level using alpha-particle emitting radionuclides. Alpha-particles have a very short range in tissues (... LÄS MER

  3. 3. Fibroblast growth factor-23 and Klotho in bone/mineral and parathyroid disorders

    Författare :Tijana Krajisnik; Tobias E. Larsson; Kenneth B. Jonsson; Östen Ljunggren; Peyman Björklund; Gunnar Sterner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; calcitriol; chronic kidney disease; CKD; chronic renal failure; fibroblast growth factor 23; fibroblast growth factor-23; FGF23; FGF-23; GalNac-T3; GALNT3; GFR; hyperostosis-hyperphosphatemia syndrome; HHS; Klotho; parathyroid hormone; PTH; hyperparathyroidism; pHPT; sHPT; uremic; vitamin D3; Endocrinology; Endokrinologi; Internal Medicine; invärtesmedicin;

    Sammanfattning : Fibroblast growth factor-23 (FGF23) is a novel, bone-produced hormone that regulates renal phosphate (Pi) reabsorption and calcitriol metabolism. Disorders of mineral and bone metabolism, such as autosomal dominant hypophosphatemic rickets (ADHR) and hyperostosis-hyperphosphatemia syndrome (HHS), witness the importance of well-balanced serum levels of FGF23. LÄS MER

  4. 4. Novel Approaches to Treatment and Prevention of Diabetic Nephropathy

    Författare :Lina Nordquist; Mats Sjöquist; Peter Bergsten; William J. Welch; Uppsala universitet; []
    Nyckelord :Physiology; Diabetes; Nephropathy; C-peptide; Microneedle; Renal; GFR; Oxygen Consumption; Reabsorption; Fysiologi;

    Sammanfattning : Several studies have reported beneficial effects of C-peptide supplementation in diabetic patients and animal models of insulinopenic diabetes. However, it is also established that good glycemic control is essential to minimize the risk of diabetes-induced complications. LÄS MER

  5. 5. Biomarkers of Renal Function in Acute Coronary Syndromes

    Författare :Axel Åkerblom; Stefan James; Lars Wallentin; Torbjörn Omland; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cystatin C; glomerular filtration rate; GFR; creatinine; acute coronary syndrome; ACS; kidney; renal; mortality; death; myocardial infarction; Cardiology; Kardiologi; Medicin; Medicine; Internal Medicine; Internmedicin;

    Sammanfattning : The thesis aimed to investigate cystatin C and creatinine-based estimates of glomerular filtration rate (eGFR), both at admission and during follow-up, on the combined endpoint of cardiovascular death and myocardial infarction in patients with acute coronary syndrome (ACS). We also evaluated two cystatin C assays and assessed genetic determinants of cystatin C concentrations. LÄS MER