Sökning: "Fredrick Lindström"

Hittade 1 avhandling innehållade orden Fredrick Lindström.

1. 1. Biological membrane interfaces involved in diseases : a biophysical study

   Författare :Fredrick Lindström; Gerhard Gröbner; Dick Sandström; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Solid-state NMR; DSC; Amyloid-beta peptide; Nociceptin; DMPC; DMPG; DDAB; peptide-lipid interaction; branched-chain fatty acid.; Biophysical chemistry; Biofysikalisk kemi;

   Sammanfattning : Interactions between peptides and biological lipid membranes play a crucial role in many cellular processes such as in the mechanism behind Alzheimer’s disease where amyloid-beta peptide (Abeta)is thought to be a key component. The initial step of binding between a surface active peptide and its target membrane or membrane receptor can involve a non specific electrostatic association where positively charged amino acid residues and a negatively charged membrane surface interact. LÄS MER