Sökning: "Fate determination"

Visar resultat 1 - 5 av 40 avhandlingar innehållade orden Fate determination.

  1. 1. Hormonal Regulation of Neural Stem Cell Proliferation and Fate Determination

    Författare :Karin Brännvall; Dan Lindholm; Sandra Ceccatelli; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neural stem cell; Proliferation; Fate determination; Hormones; Anabolic androgenic steroids; Neurovetenskap; Neurology; Neurologi;

    Sammanfattning : Stem cells have the capacity for both self renewal, and to form all cell types in the body. Interestingly, so called neural stem cells (NSCs) are found in the adult human brain, which is of significance both out of a developmental perspective and from a clinical point of view. LÄS MER

  3. 2. Fate of Pharmaceuticals and Their Transformation Products in Rivers : An integration of target analysis and screening methods to study attenuation processes

    Författare :Zhe Li; Anna Sobek; Michael McLachlan; Michael Radke; Kathrin Fenner; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; pharmaceuticals; transformation products; fate; river; suspect screening; non-target screening; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : Pharmaceuticals are environmental contaminants causing steadily increasing concern due to their high usage, ubiquitous distribution in the aquatic environment, and potential to exert adverse effects on the ecosystems. After being discharged from wastewater treatment plants (WWTPs), pharmaceuticals can undergo transformation processes in surface waters, of which microbial degradation in river sediments is considered highly significant. LÄS MER

  4. 3. Decoding the contribution of transcription factors to cell fate determination

    Författare :Bei Wei; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : It is well accepted that transcription factors (TFs) play a crucial role in determining cell identity. Although RNA expression or protein abundance data show that a large fraction of the total TFs are expressed in a given cell, however, only a small set of them is essential for specifying cell identity. LÄS MER

  5. 4. Spatial and temporal mechanisms of cell fate determination in the developing CNS

    Författare :José Dias; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The generation of neural cell diversity in the developing central nervous system relies on mechanisms that provide spatial and temporal information to neural progenitor cells. The deployment of morphogen gradients is an important strategy to impart spatial information to the field of responding cells. LÄS MER

  7. 5. Regional control of cell fate determination and neurogenesis in the developing CNS

    Författare :Ulrika Marklund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The development of a functional central nervous system relies on the generation of distinct neuronal subtypes in a spatially and temporally defined order. The spatial organisation is achieved at early developmental time points when neural progenitor cells encounter fields of secreted morphogenic signalling molecules along the anterioposterior and dorsoventral axes of the embryo. LÄS MER