Sökning: "F-Ara-A"

Hittade 1 avhandling innehållade ordet F-Ara-A.

1. 1. Targeting the nucleotide metabolism of the mammalian pathogen Trypanosoma brucei

   Författare :Munender Vodnala; Anders Hofer; Arne Holmgren; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Trypanosoma brucei; adenosine kinase; thymidine kinase; methylthioadenosine phosphorylase; mouser ribonucleotide reductase; E. coli ribonucleotide reductase; RNR; Ara-A; F-Ara-A; dNTP; NTP; doexynucleotide metabolism; nucleosides; nucleoside kinases; allosteric regulation; biologisk kemi; biological chemistry;

   Sammanfattning : Trypanosoma brucei causes African sleeping sickness in humans and Nagana in cattle. There are no vaccines available against the disease and the current treatment is also not satisfactory because of inefficacy and numerous side effects of the used drugs.T. LÄS MER