Sökning: "Excessive alcohol intake"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden Excessive alcohol intake.

1. 1. Demographic and clinical characteristics in groups of individual with exessive alcohol intake

   Författare :Kristina Berglund; Göteborgs universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Excessive alcohol intake; demography; clinical characteristics; substance use; age; gender; treatment experience;

   Sammanfattning : People who misuse alcohol are a heterogeneous group with different etiology and clinical characteristics. One aim in the field of alcohol research has been to categorise these individuals in order to study possible pathways into alcohol use disorders and the long-term course of alcoholism. LÄS MER

3. 2. Preclinical investigations of GlyT-1 inhibition as a new concept for treatment of alcohol dependence

   Författare :Helga Lidö Höifödt; Göteborgs universitet; []
   Nyckelord :Psykiatri experimentell ; Neurofarmakologi; alcohol; dependence; dopamine; GlyT-1 inhibition; nucleus accumbens; reward;

   Sammanfattning : Alcohol addiction and abuse is a main contributor to the global burden of disease and is a high public health priority. Alcohol addiction is a chronically relapsing neurobiological disorder affecting multiple neurotransmitter systems. LÄS MER

4. 3. Maternal Separation in Rats : An Experimental Model for Long-Term Effects of Early Life Experiences on Neurochemistry, Voluntary Ethanol Intake and Exploration and Risk Assessment Behavior

   Författare :Erika Roman; Ingrid Nylander; J. Dee Higley; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical pharmacology; Handling; Maternal Deprivation; Environment; Opioids; Dopamine; Alcohol; Stress; Concentric Square Field; Open Field; Elevated Plus-maze; Farmaceutisk farmakologi; Pharmaceutical pharmacology; Farmaceutisk farmakologi;

   Sammanfattning : The period of early life is important for the development of individual brain function and behavior. Human studies have shown altered vulnerability to develop psychopathology and/or excessive drug intake, possibly leading to dependence, as a consequence of early life experiences. LÄS MER

5. 4. Taurine and dopamine-related effects of ethanol. An experimental study in rodents

   Författare :Lisa Ulenius; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Addiction; Alcohol; Caffeine; Nucleus accumbens; Microdialysis;

   Sammanfattning : The reinforcing properties of alcohol (ethanol) are associated with activation of the mesolimbic dopamine system and the concomitant increase in dopamine in the nucleus accumbens (nAc). Changes in this system are thought to be a predominant underlying factor in promoting excessive alcohol intake and alcohol use disorder. LÄS MER

7. 5. Early Environment and Adolescent Ethanol Consumption : Effects on Endogenous Opioids and Behaviour in Rats

   Författare :Loudin Daoura; Ingrid Nylander; Erika Roman; Bo Söderpalm; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alcohol; intermittent ethanol access; maternal separation; multivariate concentric square field™ test; maternal behavior; ultrasonic vocalization; adolescent; neonatal handling; Farmaceutisk farmakologi; Pharmaceutical Pharmacology;

   Sammanfattning : Excessive and compulsive ethanol drinking is one of the most serious public health issues. Therefore, it is vital to increase the knowledge about risks and protection for alcohol use disorders (AUD) to optimize prevention and treatment strategies. LÄS MER