Sökning: "Esophagus"

Visar resultat 1 - 5 av 62 avhandlingar innehållade ordet Esophagus.

1. 1. The Columnar Lined Esophagus. Pathophysiological and Clinical Aspects

   Författare :Stefan Öberg; Lund Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intestinal metaplasia; Barrett s esophagus; Esophageal columnar metaplasia; Metaplasia; Pathophysiology; Gastroesophageal reflux disease; Esophagus; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : There is a persisting controversy concerning the definition, etiology and pathogenesis of Barrett's esophagus. The dramatic and parallel increase in the incidence of esophageal and junctional adenocarcinoma over the past decades justifies an evaluation of the pathophysiology of premalignant metaplastic changes of the esophagus and the gastroesophageal junction. LÄS MER

3. 2. On tissue engineering of pig, human, and non-human primate tissues

   Författare :Nikhil Nayakawde; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Decellularization; esophagus; heart; larynx; proteomics; recellularization; SILAC; stem cells; tissue engineering;

   Sammanfattning : Background: Demand for donor organs for transplantation has been increasing every year more than the actual supply of suitable donor organs. One of the major problems associated with allogeneic transplantation includes lifelong immunosuppression. LÄS MER

4. 3. Aspects on endoscopic characterization and clinical management of Barrett's esophagus

   Författare :Francisco Baldaque Silva; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Barrett’s esophagus;

   Sammanfattning : Barrett's esophagus (BE) is considered to result from prolonged gastroesophageal reflux and is the only known precursor of esophageal adenocarcinoma. The clinical management of BE patients aims to control esophageal reflux to reduce mucosal injury and neoplastic progression, and to detect early neoplastic lesions in Barrett’s mucosa, suitable for curative endoscopic treatment. LÄS MER

5. 4. The Columnar Lined Esophagus: aspects on the assessment of dysplasia and on the relationship with the esophageal submucosal glands

   Författare :Ester Lörinc; Malmö Klinisk patologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Columnar lined esophagus; Barrett´s esophagus; submucosal gland; multilayered epithelium; p53; Ki67; CK17; skin appendage;

   Sammanfattning : Columnar metaplasia, where columnar epithelium replaces the normal squamous epithelium in esophagus, is considered to be a precancerous condition in which the development of adenocarcinoma can be followed through various grades of dysplasia. The interpretation of these histological changes is subjective and suffers from considerable inter-observer variation among pathologists. LÄS MER

7. 5. p53 and neoplastic progression in Barrett's esophagus

   Författare :Stig Ramel; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Barrett s esophagus; neoplastic progression; flow cytometry; p53 gene; p53protein; 17p allelic loss; p53 mutations; S phase fractions; aneuploidy; SV 40 large T antigen; elastase-SV 40 T antigen transgenic mice.;

   Sammanfattning : Barrett's esophagus is a condition in which the normal squamous epithelium is replaced by columnar epithelium as a response to acid reflux. It develops as a complication in 10-20% of patients with gastroesophageal reflux disease. LÄS MER