Sökning: "Erik Simonsson"

Hittade 4 avhandlingar innehållade orden Erik Simonsson.

  1. 1. On Cholecystokinin and Phospholipase A2 in Insulin Secretion - an Experimental Study With Reference to the Development of Diabetes

    Författare :Erik Simonsson; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Insulin Resistance; Islet; Beta-cell; Insulin Secretion; Ca2 -Dependency; Intracellular Signalling; Phospholipase A2; Cholecystokinin; Non-glucose Secretagogues; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : In view of unsolved issues regarding cellular events underlying the adaptation of insulin secretion to insulin resistance, together with the observation that insulin secretion induced by the gastrointestinal hormone and neuropeptide cholecystokinin (CCK) is not solely explained by phospholipase C-protein kinase C (PLC-PKC) pathway activation, this study aimed at delineate mechanisms responsible for the hyperinsulinemia in insulin resistance, with particular attention paid to the action of glucose vs. non-glucose secretagogues, such as CCK. LÄS MER

  3. 2. Modelling of fatigue crack propagation in Inconel 718 under hold time conditions

    Författare :Erik Lundström; Kjell Simonsson; Tomas Månsson; David Gustafsson; Johan Moverare; Martin Hughes; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : In this thesis an investigation and modelling of the fatigue crack propagation in the nickel based superalloy Inconel 718, with a special emphasis on the effect of hold times, is presented. The modelling work has been concentrated on describing the hold time fatigue crack propagation by using the concept of a damaged zone in front of the crack tip, which is believed to have a lowered resistance against crack propagation. LÄS MER

  4. 3. High Temperature Fatigue Crack Growth in a Ni-based Superalloy : Modelling Including the Interaction of Dwell Times

    Författare :Erik Storgärds; Kjell Simonsson; Johan Moverare; Tomas Månsson; Bo Alfredsson; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Safe life of gas turbines is always of major concern for manufacturers in order to ensure passenger safety and stable continuous power output. An increasing amount of resources have been put into research and development to assure that all safety aspects are covered in the design of new turbines and to ensure that enough frequent service intervals are scheduled to avoid complications. LÄS MER

  5. 4. Jämlikhet och valfrihet : en studie av den svenska invandrarpolitikens framväxt

    Författare :Lars-Erik Hansen; Birger Simonsson; Stockholms universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; historia; History;

    Sammanfattning : The objectives of this dissertation are to study the beliefs about immigrant minorities and immigration policy expressed in Swedish public debate and politics and to study how Swedish immigration policy emerged and took on its distinctive shape, from the first immigration policy initiatives through the resolutions on immigration policy adopted by the Riksdag in 1975 and 1976.The dissertation shows, through studies of public debates, that equality gained unique status in Sweden. LÄS MER