Sökning: "Elena Sandalova"

Hittade 1 avhandling innehållade orden Elena Sandalova.

1. 1. Regulation of the pro-apoptotic protein Bim by T cell receptor triggering in human T cells

   Författare :Elena Sandalova; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Bim; Apoptosis; Mitochondria; CTLs; AICD; TCR activation;

   Sammanfattning : Bim is a significant pro-apoptotic member of Bcl-2 family of proteins; it is proved to be an important regulator of apoptosis: over the years it has been shown to play a pivotal role for the development and maintenance of homeostasis in many cellular systems and tissues. The Bcl-2 family of proteins is a group of key regulators of the mitochondrial, or intrinsic, pathway of apoptosis. LÄS MER