Sökning: "ESBLs"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet ESBLs.

  1. 1. Mechanisms and Dynamics of Carbapenem Resistance in Escherichia coli

    Författare :Marlen Adler; Linus Sandegren; Josep Casadesús; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; carbapenem; antibiotic resistance; fitness cost; ESBLs; penicillin-binding proteins; gene amplification;

    Sammanfattning : The emergence of extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae worldwide has led to an increased use of carbapenems and may drive the development of carbapenem resistance. Existing mechanisms are mainly due to acquired carbapenemases or the combination of ESBL-production and reduced outer membrane permeability. LÄS MER

  3. 2. Antimicrobial Resistance and Production of Extended Spectrum Beta-Lactamases in Enterobacteriaceae from Birds in Bangladesh

    Författare :Badrul Hasan; Björn Olsen; Åsa Melhus; Yvonne Agersø; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antimicrobial Resistance; ESBL; CTX-M; NDM; Poultry; Wild birds; E. coli; Bangladesh; Enterobacteriaceae; Antibiotics; Epidemiology; Epidemiologi; Mikrobiologi; Microbiology; Medical Science; Medicinsk vetenskap;

    Sammanfattning : The dissemination of members of the Enterobacteriaceae family with extended spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs) has become a global concern. ESBLs and MBLs have been reported in humans, domestic animals, wildlife and the environment, and their isolation frequencies are increasing rapidly worldwide. LÄS MER

  4. 3. Enterobacteriaceae Producing Extended-Spectrum Beta-Lactamases : Aspects of Detection, Epidemiology and Control

    Författare :Birgitta Lytsy; Åsa Melhus; Dan Andersson; Håkan Hanberger; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extended-spectrum beta-lactamase; ESBL; pulse-field gel elctrophoresis; typing methods; infection control; typningsmetoder; vårdhygien; Bacteriology; Bakteriologi; Clinical Bacteriology; Klinisk bakteriologi;

    Sammanfattning : Enterobacteriaceae belong to the normal enteric flora in humans and may cause infections. Escherichia coli is the leading urinary tract pathogen with septicaemic potential, whereas Klebsiella pneumoniae causes opportunistic infections and often outbreaks in hospital settings. LÄS MER

  5. 4. Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae : Treatment, Selection and International Spread

    Författare :Thomas Tängdén; Otto Cars; Anders Johansson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; Klebsiella pneumoniae; extended-spectrum beta-lactamases; carbapenemases; metallo-beta-lactamases; synergy; antibiotic interventions;

    Sammanfattning : The prevalence of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases (ESBLs) and carbapenemases is increasing worldwide. Therapeutic options for infections with these bacteria are limited not only by the production of ESBLs and carbapenemases, which confer resistance to cephalosporins and carbapenems, but also by frequent co-resistance to other antibiotics. LÄS MER

  7. 5. Extremely drug resistant E. coli and K. pneumoniae : novel approaches against their spread and related infections

    Författare :Angela Camporeale; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antibiotic resistance in Enterobacteriaceae is a well-established hindrance and the spread of pathogenic high-risk clones harboring extended-spectrum -lactamases (ESBLs) and carbapenemases is posing a global health challenge, due to very less treatment alternatives. Particular lineages from the major representative species E. coli and K. LÄS MER